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Mild Cryotherapy for Prevention of Paclitaxel-Induced Nail Toxicity in Breast Cancer Patients: A Phase II Single-Arm Clinical Trial.
Clin Breast Cancer
June 2023
Unit of Medical Oncology and Cancer Prevention, Department of Medical Oncology, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, PN, Italy; Department of Medicine, University of Udine, Udine, Italy.
Background: Nail changes are among the most common dermatological adverse events in paclitaxel-receiving patients. Although effective, low-temperature prophylactic cryotherapy is discomforting and a potential cause of side effects, resulting in low patients' adherence.
Patients And Methods: A phase II single-arm study evaluating mild cryotherapy for the reduction of 12-week, grade 2 nail toxicity was conducted on 67 taxane-naïve breast cancer patients (age 18-74 years) undergoing weekly adjuvant chemotherapy with paclitaxel.
A case of ice-pack dermatosis in a patient with chronic back pain and review of the literature.
Int J Dermatol
June 2023
Department of Dermatology, University of California, Irvine, CA, USA.
[Chronic brachioradial pruritus in cervical spine meningioma].
Hautarzt
June 2022
Kompetenzzentrum chronischer Pruritus (KCP), Klinik für Hautkrankheiten, Universitätsklinikum Münster, Von-Esmarch-Str. 58, 48149, Münster, Deutschland.
Article Synopsis
- A 57-year-old woman experienced localized itching on her arms, which also included stinging and burning sensations, and had some skin irritation noted during examination.
- MRI scans showed she had a meningioma (a type of tumor) at the C5/C6 level of her cervical spine, leading to the diagnosis of brachioradial pruritus due to compression of the spinal cord.
- Other potential causes for her condition could include issues like disc herniation, foraminal stenosis, or degenerative changes in the spine.
Non-Invasive Analysis of Actinic Keratosis before and after Topical Treatment Using a Cold Stimulation and Near-Infrared Spectroscopy.
Medicina (Kaunas)
September 2020
PoliToBIOMed Lab, Biolab, Department of Electronics and Telecommunications, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy.
: The possible evolution of actinic keratoses (AKs) into invasive squamous cell carcinomas (SCC) makes their treatment and monitoring essential. AKs are typically monitored before and after treatment only through a visual analysis, lacking a quantitative measure to determine treatment effectiveness. Near-infrared spectroscopy (NIRS) is a non-invasive measure of the relative change of oxy-hemoglobin and deoxy-hemoglobin (OHb and HHb) in tissues.
View Article and Find Full Text PDFIce-pack dermatosis of the buttocks.
Int J Dermatol
November 2020
Department of Dermatology, Mayo Clinic, Rochester, MN, USA.
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