AI Article Synopsis

  • A 4-month-old breast-fed girl with poor weight gain exhibited edema and repeated skin inflammation, leading to a diagnosis of protein-losing enteropathy (PLE) confirmed via scintigraphy.
  • Specific IgE tests indicated an allergy to egg proteins, prompting the mother to eliminate eggs from her diet.
  • Following this change and treatment, the infant showed improvement in symptoms, suggesting that IgE-mediated food allergies could significantly contribute to PLE in breast-fed infants.

Article Abstract

A 4-month-old breast-fed girl presented with poor weight gain, and had edema and repeated erythema from 5 months of age. The diagnosis of protein-losing enteropathy (PLE) was confirmed on Tc-labeled human serum albumin scintigraphy. Specific IgE radioallergosorbent test was class 3 for egg white, class 2 for egg yolk, and negative for other foods. Elimination of egg from the mother's diet and oral epinastine hydrochloride treatment and sodium cromolyn improved hypoalbuminemia, hypogammaglobulinemia, and erythema. PLE and erythema coincident in a breast-fed infant suggests that IgE-mediated allergy may play a leading role in some cases of PLE due to food allergy in infants.

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http://dx.doi.org/10.1111/ped.12824DOI Listing

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