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C-X-C motif chemokine receptor 4-directed PET signal in the arterial tree is not consistently linked to calcified plaque burden and cardiovascular risk.
Theranostics
January 2025
Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
To establish the extent, distribution and frequency of in-vivo vessel wall [Ga]Ga-PentixaFor uptake and to determine its relationship with calcified atherosclerotic plaque burden (CAP) and cardiovascular risk factors (CVRF). 65 oncological patients undergoing [Ga]Ga-PentixaFor PET/CT were assessed. Radiotracer uptake (target-to-background ratio [TBR]) and CAP burden (including number of CAP sites, calcification circumference and thickness) in seven major vessel segments per patient were determined.
View Article and Find Full Text PDFD-Dimers and MPO Are No Suitable Biomarkers for Application in Abdominal Aortic Aneurysm (AAA) Surveillance in a Real-World Setting of Vascular Surgery Patients.
Biomolecules
November 2024
Klinik für Gefäßchirurgie und Endovaskuläre Chirurgie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany.
There is currently no clinically valid biomarker for predicting the growth and prognosis of abdominal aortic aneurysms (AAA). The most promising candidates with the highest diagnostic values are plasma D-dimers and markers of activated neutrophils, i.e.
View Article and Find Full Text PDFMolecular imaging along the heart-kidney axis.
Theranostics
December 2024
Goethe University Frankfurt, University Hospital, Department of Nuclear Medicine, Clinic for Radiology and Nuclear Medicine, Frankfurt, Germany.
Article Synopsis
- Cardiorenal syndrome (CRS) is a complex condition characterized by the interaction between heart and kidney failures, where issues in one organ can exacerbate the other.
- Molecular imaging techniques like SPECT and PET can help us understand the underlying processes, such as inflammation and fibrosis, affecting both organs.
- The findings from these imaging methods may improve patient care by providing prognostic information and guiding targeted treatments for cardiorenal issues.
Anatomical Suitability of Iliac Branch Devices for East Asian Patients with Abdominal Aortic Aneurysm.
Eur J Vasc Endovasc Surg
September 2024
Department of Vascular and Endovascular Surgery, Chinese PLA General Hospital, Beijing, China. Electronic address:
Objective: This study aimed to identify the iliac artery characteristics of East Asian patients with abdominal aortic aneurysms (AAAs) and to evaluate anatomical suitability rates with current iliac branch devices (IBDs).
Methods: This was a single centre, retrospective, cross sectional study. Patients diagnosed with AAA between 2008 and 2023 were enrolled.
Endovascular Conversion of a Failed Nellix AAA-Repair by a Custom-Made Branched Device.
J Endovasc Ther
August 2024
Department of Vascular and Endovascular Surgery, St. Franziskus-Hospital Muenster, Munster, Germany.
Purpose: This technical note presents a case of a patient with a failed Nellix device (Endologix, Irvine, Calif) who was not deemed fit for open conversion. Our planned approach for repair involved an endovascular procedure utilizing a custom-made branched device.
Technique: An endovascular repair was performed via a custom-made four outer branched device in conjunction with a custom-made bifurcated graft featuring inverted limbs (Cook Inc.
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