AI Article Synopsis
- Turner syndrome (TS) is a chromosomal disorder that can lead to various cardiovascular issues, with vascular abnormalities being particularly common.
- The case of a 9-year-old girl with TS, who experienced weakness in her legs due to spinal hemorrhage from a vascular malformation, highlights the rare occurrence of vertebral artery dissection in TS.
- Immediate treatment with high-dose dexamethasone improved her ability to walk, emphasizing the importance of rapid diagnosis and MRI for suspected spinal vessel rupture in TS patients.
Article Abstract
Turner syndrome (TS) is a relatively common chromosomal disorder and is associated with a range of comorbidities involving the cardiovascular system. Vascular abnormalities, in particular, are a common finding in cases of TS. However, dissection involving the vertebral arteries is rare. Here, we report the case of a 9-year-old girl with TS who had been treated with growth hormone replacement therapy for the past 3 years. She presented with weakness of both lower legs, and was ultimately diagnosed with spinal hemorrhage due to vascular malformation. We treated her with intravenous high dose dexamethasone (0.6 mg/kg) and she could walk without assistance after 6 days of treatment. In conclusion, when a patient with TS shows sudden weakness of the lower limbs, we should consider the possibility of spinal vessel rupture and try to take spine magnetic resonance imaging as soon as possible. We suggest a direction how to make a proper diagnosis and management of sudden vertebral artery hemorrhage in patients with TS.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722165 | PMC |
| http://dx.doi.org/10.6065/apem.2015.20.4.235 | DOI Listing |
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