Atrial Natriuretic Peptide in the High Normal Range Is Associated With Lower Prevalence of Insulin Resistance.

J Clin Endocrinol Metab

Departments of Cardiology (A.J., M.M.), Internal Medicine (O.M.), and Clinical Sciences (A.J., P.M.N., M.P., L.G., O.M., M.M.), Skåne University Hospital, SE-205 02 Malmö, Sweden; Department of Clinical Sciences (V.L.), Diabetes and Endocrinology Unit, Lund University Diabetes Center, Lund University, SE-200 41 Malmö, Sweden; Department of Biomedical Sciences and NNF Center for Basal Metabolic Research (J.J.H., S.S.T.), The Panum Institute, DK-2200 Copenhagen, Denmark; and Steno Diabetes Center A/S (V.L.), DK-2820 Gentofte, Denmark.

Published: April 2016

In 2243 subjects, MR-proANP was measured at baseline. At follow up, MR-proANP levels in the high normal range were associated with lower prevalence of insulin resistance and higher post challenge GIP secretion.

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http://dx.doi.org/10.1210/jc.2015-3518DOI Listing

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