Objective: To investigate the molecular epidemiology of acinetobacter baumannii and pseudomonas aeruginosa isolated from clinical specimens from patients on mechanical ventilation.
Methods: From October to December, 2012, acinetobacter baumannii and pseudomonas aeruginosa strains were isolated from patients on mechanical ventilation. Antibiotic susceptibility data of all strains was collected. Homology of the strains was analyzed by the methods of pulsed field gel electrophoresis (PFGE) genotype, meanwhile, the clinical data was also analyzed.
Results: Of the 15 pathogens isolated from patients on mechanical ventilation, 7 acinetobacter baumannii strains had different genotypes, indicating specific clustering in a specific location, so acinetobacter baumannii should be a scattered infection or colonized strains. Parts of 8 pseudomonas aeruginosa strains came from the same clone and confirm the existence of cross-infection of nosocomial infections.
Conclusion: The result shows that nosocomial infection outbreak doesn't occur, there is a small range of cross-infection of pseudomonas aeruginosa.
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