Impact of host genetic polymorphisms on vaccine induced antibody response.

Hum Vaccin Immunother

a Applied Microbiology Research , Department of Biomedicine, University Basel, Basel , Switzerland.

Published: April 2016

Many host- and vaccine-specific factors modulate an antibody response. Host genetic polymorphisms, in particular, modulate the immune response in multiple ways on different scales. This review article describes how information on host genetic polymorphisms and corresponding immune cascades may be used to generate personalized vaccine strategies to optimize the antibody response.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962936PMC
http://dx.doi.org/10.1080/21645515.2015.1119345DOI Listing

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