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Willingness to Use Long-Acting Injectable Pre-Exposure Prophylaxis among Adolescent Girls and Young Women in Kampala, Uganda.
AIDS Behav
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Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine (MRC/UVRI & LSHTM) Uganda Research Unit, Kampala, Uganda.
Pre-exposure prophylaxis (PrEP) has proven to be a powerful tool in preventing HIV infection. There is limited information about the factors associated with willingness to use different PrEP modalities among adolescent girls and young women (AGYW) in Africa. We assessed willingness to use long-acting injectable PrEP (LAI-PrEP) among 14-24-year-old AGYW at high risk of HIV in Uganda, and associated factors determined using multivariable complementary log-log regression.
View Article and Find Full Text PDFVopX, a novel T3SS effector, modulates host actin dynamics.
mBio
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Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA.
Unlabelled: Pathogenic strains cause cholera using different mechanisms. O1 and O139 serogroup strains use the toxin-co-regulated pilus (TCP) and cholera toxin (CT) for intestinal colonization and to promote secretory diarrhea, while non-O1/non-O139 serogroup strains are typically non-toxigenic and use alternate virulence factors to cause a clinically similar disease. An O39 serogroup, TCP/CT-negative strain, named AM-19226, uses a type III secretion system (T3SS) to translocate more than 10 effector proteins into the host cell cytosol.
View Article and Find Full Text PDFLensless imaging offers a lightweight, compact alternative to traditional lens-based systems, ideal for exploration in space-constrained environments. However, the absence of a focusing lens and limited lighting in such environments often results in low-light conditions, where the measurements suffer from complex noise interference due to insufficient capture of photons. This study presents a robust reconstruction method for high-quality imaging in low-light scenarios, employing two complementary perspectives: model-driven and data-driven.
View Article and Find Full Text PDFInvestigating time-independent and time-dependent diffusion phenomena using steady-state diffusion MRI.
Sci Rep
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Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Diffusion MRI is a leading method to non-invasively characterise brain tissue microstructure across multiple domains and scales. Diffusion-weighted steady-state free precession (DW-SSFP) is an established imaging sequence for post-mortem MRI, addressing the challenging imaging environment of fixed tissue with short T and low diffusivities. However, a current limitation of DW-SSFP is signal interpretation: it is not clear what diffusion 'regime' the sequence probes and therefore its potential to characterise tissue microstructure.
View Article and Find Full Text PDF2D Surface Optical Reflectance for use in Harsh Reactive Environments.
J Phys Condens Matter
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Department of Physics, Lund University, BOX 118, Lund, 221 00, SWEDEN.
In recent years, studies of surfaces at more realistic conditions has advanced significantly, leading to an increased understanding of surface dynamics under reaction conditions. The development has mainly been due to the development of new experimental techniques or new experimental approaches. Techniques such as High Pressure Scanning Tunneling/Force Microscopy (HPSTM/HPAFM), Ambient Pressure X-ray Photo emission Spectroscopy (APXPS), Surface X-Ray Diffraction (SXRD), Polarization-Modulation InfraRed Reflection Absorption Spectroscopy (PMIRRAS) and Planar Laser Induced Fluorescence (PLIF) at semi-realistic conditions has been used to study planar model catalysts or industrial materials under operating conditions.
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