AI Article Synopsis

  • Reports on pancreas-preserving total duodenectomy (PPTD) for duodenal polyposis (DP) in familial adenomatous polyposis (FAP) patients are rare, but this case showcases a successful procedure performed on a 27-year-old female.
  • The patient was diagnosed with Spigelman classification stage IV DP and underwent PPTD through a small incision, with pathology confirming all polyps as adenomas.
  • After six months of follow-up, the patient did not experience common complications associated with total duodenectomy, suggesting that PPTD may be a safer and more suitable option for young female patients with non-advanced duodenal cancers.

Article Abstract

Introduction: Reports on pancreas-preserving total duodenectomy (PPTD) for duodenal polyposis (DP) in familial adenomatous polyposis (FAP) patients are rare. We herein report a case of PPTD performed by minilaparotomy for DP in an FAP patient.

Case: A 27-year-old female FAP patient was diagnosed with Spigelman classification (SC) stage Ⅳ DP on gastroduodenoscopy. She underwent PPTD through a 7 cm upper abdominal incision. All polyps were confirmed as adenomas histopathologically. After 6 months of follow-up, complications related to total duodenectomy, such as weight loss, diabetes mellitus, and fatty liver have not been observed.

Discussion: SC stage Ⅳ refers to non-advanced cancers, and PPTD is basically prophylactic surgery. Therefore, pancreatoduodenectomy seems too aggressive for SC stage Ⅳ patients. PPTD by minilaparotomy is suitable for young female patients for its curability, esthetic outcome, and safety.

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