Background: Perioral wrinkling is commonly reported among older adults, but its objective evaluation and causes remain poorly understood.

Objective: We sought to develop a photonumeric scale for perioral wrinkling and to elucidate contributory lifestyle factors.

Methods: In this cross-sectional study, we recruited participants for facial photographs and a survey. A gender-specific photonumeric scale for perioral wrinkling was developed and used by 3 graders to evaluate participant photographs. Scores and survey responses were used to create a multiple regression model to predict perioral wrinkling.

Results: In all, 143 participants aged 21 to 91 years were enrolled. Intraclass correlation coefficient values for interrater and intrarater reliability were high (>0.8) across 2 trials and 3 graders. A multiple regression model for prediction of perioral wrinkling severity included age, gender, and years of smoking as variables.

Limitations: The study was limited by sample size and a predominantly Caucasian study population.

Conclusion: We created a photonumeric scale that accounts for gender differences in perioral wrinkling and highlighted contributory variables to photoaging in this anatomical location.

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http://dx.doi.org/10.1016/j.jaad.2015.11.042DOI Listing

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