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Insulin dependence as an independent predictor of complications following surgical treatment of distal radius fracture.
Eur J Orthop Surg Traumatol
January 2025
Stony Brook University Hospital, Stony Brook, USA.
Purpose: Diabetes mellitus (DM) is a well-established risk factor for postoperative complications. Distal radius fractures (DRFs) are a common orthopedic injury and often require open reduction and internal fixation (ORIF). The rise of ORIF utilization warrants investigation into factors that may expose patients to postoperative complications following DRF ORIF.
View Article and Find Full Text PDFThe protective roles of eugenol on type 1 diabetes mellitus through NRF2-mediated oxidative stress pathway.
Elife
January 2025
Department of Pediatrics, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Type 1 diabetes mellitus (T1DM), known as insulin-dependent diabetes mellitus, is characterized by persistent hyperglycemia resulting from damage to the pancreatic β cells and an absolute deficiency of insulin, leading to multi-organ involvement and a poor prognosis. The progression of T1DM is significantly influenced by oxidative stress and apoptosis. The natural compound eugenol (EUG) possesses anti-inflammatory, anti-oxidant, and anti-apoptotic properties.
View Article and Find Full Text PDFAim: To study the associations between risk factors, clinical characteristics, severity of brachiocephalic artery (BCA) atherosclerosis and severity of coronary artery (CA) disease in patients with acute coronary syndrome (ACS).
Material And Methods: The study included patients with any type of ACS and obstructive coronary artery disease confirmed by coronary angiography. A quantitative analysis of coronary angiography data was performed with an assessment of the number of CAs with significant stenosis and calculation of the SYNTAX score.
Middle segment preserving pancreatectomy versus total pancreatectomy: a comparative analysis of short- and long-term outcomes.
Surg Today
December 2024
Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Purpose: Middle-segment preserving pancreatectomy (MSPP) serves as an alternative to total pancreatectomy (TP) for preserving the pancreatic body in multifocal pancreatic neoplasms. Despite the potential benefits of TP, the detailed short- and long-term prognoses remain unclear. We evaluated the feasibility of MSPP by comparing the perioperative outcomes and postoperative endocrine and exocrine functions with those of TP.
View Article and Find Full Text PDFChronic corticosteroid use does not increase short-term complications following carpometacarpal arthroplasty.
Eur J Orthop Surg Traumatol
November 2024
Department of Orthopaedics, Stony Brook University Hospital, HSC T-18, Room 080, Stony Brook, NY, 11794-8181, USA.
Article Synopsis
- Chronic steroid use has been linked to postoperative complications after surgeries, but this study examines its impact specifically on carpometacarpal (CMC) arthroplasty.
- Researchers analyzed records from the American College of Surgeons database, finding that out of 6432 patients, only 223 were chronic steroid users, and they had certain demographic and health indicators associated with more complications.
- The study concluded that, although chronic steroid users had slightly higher rates of some complications, these differences were not statistically significant, indicating no strong link between chronic steroid use and postoperative complications after CMC arthroplasty.
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