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An electrolyte disturbance masquerading as a panic attack.
JAAPA
January 2025
Anne Wildermuth is an assistant professor in the School of Medicine at the Uniformed Services University in Bethesda, Md., and practices in emergency medicine with MedStar Emergency Physicians in Clinton, Md. At the time this article was written, Meagan Lantz and Erin Sagers were students in the PA program at the George Washington University in Washington, D.C. Ms. Lantz now practices in cardiothoracic surgery at Stanford Health Care in Palo Alto, Calif. Ms. Sagers now practices in orthopedics at EmergeOrtho Coastal Region in Wilmington, N.C. The authors have disclosed no potential conflicts of interest, financial or otherwise. The views expressed in this article are those of the authors and not of the Department of Defense, Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., or other federal agencies.
Because proton pump inhibitors (PPIs) are so commonly used, their safety and potential adverse reactions often are not considered. This article describes a patient whose paresthesias and severe muscle cramps were attributed to panic attacks but actually were caused by hypocalcemia secondary to PPI-induced hypomagnesemia. This case serves as a reminder that PPIs should be used cautiously and appropriately with consideration for regular monitoring of electrolytes and vitamin B12.
View Article and Find Full Text PDFAssociation between magnesium and vitamin D status in adults with high prevalence of vitamin D deficiency and insufficiency.
Eur J Nutr
December 2024
Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, 8036, Austria.
Purpose: It has been assumed that magnesium (Mg) status may interact with vitamin D status. We therefore aimed at investigating the association between Mg and vitamin D status in a large cohort of adult individuals with a high prevalence of deficient/insufficient vitamin D and Mg status.
Methods: We used data from the Ludwigshafen Risk and Cardiovascular Health Study (n = 2,286) to analyze differences according to serum Mg status in circulating 25-hydroxyvitamin D [25(OH)D] (primary endpoint), 24,25-dihydroxyvitamin D [24,25(OH)D], vitamin D metabolite ratio and calcitriol, and odds ratios for deficient or insufficient 25(OH)D (secondary endpoints).
Pediatric hypoparathyroidism: etiological and clinical evaluation in a tertiary center.
Endocrine
November 2024
Department of Pediatric Endocrinology, Basaksehir Cam and Sakura City Hospital, Istanbul, Türkiye.
Purpose: This study aims to evaluate the etiology, clinical presentation, and management of pediatric hypoparathyroidism in a tertiary center.
Methods: A retrospective review was conducted on pediatric patients diagnosed with hypoparathyroidism at the Pediatric Endocrinology Clinic from March 2021 to June 2023. Data on demographic characteristics, presenting symptoms, laboratory findings, genetic analyses, and treatment outcomes were collected.
Association of Biomarkers with the Severity of Depression.
Indian J Psychol Med
September 2024
Dept. of Psychiatry, Gandhi Medical College and Hospital, Secunderabad, Telangana, India.
Background: The pathogenesis of depression remains elusive and uncertain. The literature suggests that low-grade systemic inflammation might contribute to the etiology of depression. Other markers that are studied are serum magnesium and serum cortisol.
View Article and Find Full Text PDFBone and vascular effects of magnesium supplements in CKD patients (the MagicalBone Pilot Study).
Nefrologia (Engl Ed)
November 2024
Nephrology Service, Reina Sofia University Hospital, Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC), University of Cordoba, Spain; RICORS2040, Madrid, Spain.
Background And Objective: The progression of chronic kidney disease (CKD) involves the development of alterations in mineral metabolism that are closely related to cardiovascular outcomes and bone disease. Hypomagnesemia is associated with more rapid progression of CKD and other comorbidities. Our objective was to analyze in CKD patients stages 3-4 the impact of the administration of magnesium (Mg) carbonate on bone mineral density (BMD) and hemodynamic changes associated with by vascular calcification (VC).
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