Manual calculation of bolus insulin dosages can be challenging for individuals treated with multiple daily insulin injections (MDI) therapy. Automated bolus calculator capability has recently been made available via enhanced blood glucose meters and smartphone apps. Use of this technology has been shown to improve glycemic control and reduce glycemic variability without changing hypoglycemia; however, the clinical utility of app-based bolus calculators has not been demonstrated. Moreover, recent evidence challenges the safety and efficacy of these smartphone apps. Although the ability to automatically calculate bolus insulin dosages addresses a critical need of MDI-treated individuals, this technology raises concerns about efficacy of treatment and the protection of patient safety. This article discusses key issues and considerations associated with automated bolus calculator use.
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http://dx.doi.org/10.1177/1932296815626457 | DOI Listing |
J Appl Clin Med Phys
December 2024
Department of Physics and Atmospheric Sciences, Dalhousie University, Halifax, Canada.
Purpose: In radiotherapy, body contour inaccuracies may compromise the delineation of adjacent structures and affect calculated dose. Here, we evaluate the un-editable body contours auto-generated by Ethos versions 1.0 (v1) and 2.
View Article and Find Full Text PDFJ Nucl Med
January 2025
Institute of Neuroscience and Medicine, Molecular Organization of the Brain (INM-2), Forschungszentrum Jülich, Jülich, Germany;
In animal studies it has been observed that the inhibitory neuromodulator adenosine is released into the cerebral interstitial space during hypoxic challenges. Adenosine's actions on the A adenosine receptor (AAR) protect the brain from oxygen deprivation and overexertion through adjustments in cerebral blood flow, metabolism, and electric activity. Using 8-cyclopentyl-3-(3-[F]fluoropropyl)-1-propylxanthine ([F]CPFPX), a PET tracer for the AAR, we tested the hypothesis that hypoxia-induced adenosine release reduces AAR availability in the human brain.
View Article and Find Full Text PDFJ Dairy Sci
December 2024
SimHerd A/S, Niels Pedersens Alle 2, 8300, Denmark.
The study investigates the economics of sensor-assisted dairy health management and indicates a certain economic potential in the use of a commercial rumen bolus capable of tracking activity and core body temperature. The economic evaluation was performed applying a stochastic model with the net return (NR) of investment of the sensor system as the target variable. The calculated NR considers the gross margin (GM) for both sensor-assisted and visual health monitoring, time savings through sensor-assisted monitoring, additional time spent addressing false positive messages from the sensor system, labor costs, and all costs associated with the investment in the sensor system.
View Article and Find Full Text PDFPain Physician
November 2024
Department of Anesthesiology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Department of Anesthesiology, Guizhou Provincial People's Hospital, Shanghai Children's Medical Center Guizhou Hospital, Guizhou, China.
Background: Remimazolam and propofol can be used interchangeably for general anesthesia. However, no dosing recommendations exist for the intravenous bolus administration of remimazolam during general anesthesia induction in pediatric patients. Determining the appropriate dose for anesthesia induction in pediatric patients is crucial for safe and effective surgical procedures.
View Article and Find Full Text PDFFront Clin Diabetes Healthc
November 2024
Faculty of Medicine Banja Luka, University of Banja Luka, Banja Luka, Bosnia and Herzegovina.
Unlabelled: The purpose of the study is to investigate the importance of education and re-education for the proper use of the insulin pump (IP) in order to maintain stable glycemic control over an extended period.
Methods: The study was designed as a cross-sectional retrospective study. A total of 168 patients participated in a five-day structured education program in a small group.
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