Wheeling and Dealing With Antigen Presentation in Tuberculosis.

Trends Microbiol

CNRS, IPBS (Institut de Pharmacologie et de Biologie Structurale), 205 route de Narbonne BP 64182, 31000 Toulouse, France; Université de Toulouse, UPS, IPBS, 31000 Toulouse, France. Electronic address:

Published: March 2016

In tuberculosis, antigens are transferred from infected to uninfected dendritic cells. Does this favor T lymphocyte response and anti-mycobacterial host defense? In a recent report published in Cell Host & Microbe, Ernst and colleagues show that Mycobacterium tuberculosis seems to have hijacked this mechanism for its own benefit.

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http://dx.doi.org/10.1016/j.tim.2016.01.001DOI Listing

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