Default Mode Network Functional Reorganization During Early Abstinence in Polysubstance-Using Emerging Adults Treated for Opioid Dependence.

J Neuropsychiatry Clin Neurosci

From the Division of Alcohol and Drug Abuse, McLean Hospital, Belmont, MA (MLC, JSP, KHF, GDV, BdeBF, SEL, RDW, ACJ); and the Dept. of Psychiatry, Harvard Medical School, Boston, MA (MLC, JSP, GDV, BdeBF, SEL, RDW, ACJ).

Published: January 2016

This study examined default mode network connectivity within the first 30 days of abstinence in emerging adults entering treatment for opioid dependence. There were significant associations between abstinence duration and coupling strength with brain regions within and outside of the network.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956593PMC
http://dx.doi.org/10.1176/appi.neuropsych.15090240DOI Listing

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