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Safety and Effectiveness of a New 532 nm, Long Pulse-Duration, Variable Pulse Structure Laser for Treatment of Poikiloderma of Civatte.
Lasers Surg Med
January 2025
Main Line Center for Laser Surgery, Ardmore, Pennsylvania, USA.
Background: Poikiloderma of Civatte is a benign skin condition characterized by reticulate erythema and hyperpigmentation in sun-exposed areas, predominantly on the neck, cheeks, and chest. Chronic UV exposure leads to vascular proliferation and red cell extravasation resulting in hemosiderin and melanin deposition. While many light-based modalities have been utilized to treat the disorder, the significant vascularity makes it ideally suited for treatment with vascular lasers.
View Article and Find Full Text PDFObservational Study with a New Portable Cryosurgery Device, HYDROZID, in Superficial Epidermal Lesions: An Indian Experience.
Indian J Dermatol
October 2024
Consultant Dermatologists, Srishti Clinic Dermatology and Aesthetic Centre, Thane, Maharashtra, India.
Background: Cryosurgery remains an important treatment modality in dermatology practice. HYDROZID, a new portable cryosurgery medical device using norflurane as a cryogen, was recently introduced in the Indian market. This paper reports the findings of the phase IV study conducted in India.
View Article and Find Full Text PDFSteerable Interfacial Assembly of 1D Amyloid-Like Protein Nanocomposites for Enhanced Nanoherbicide Utilization.
Small
November 2024
School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, 212013, P. R. China.
Conventional herbicide formulations suffer from serious problems such as easy drift, run-off and scouring into the environment, which pose enormous threats to human health and environmental safety. Herein, an innovative strategy is proposed to prepare oil-in-water nanoemulsions with long-term stability, enhanced droplet deposition, and improved nanoherbicide adhesion via steerable interfacial assembly of 1D amyloid-like protein nanocomposites. Bovine serum albumin (BSA) undergoes rapid amyloid-like aggregation upon reduction of its disulfide bond.
View Article and Find Full Text PDFDemonstration of charge-hold-vent (CHV) and no-vent-fill (NVF) in a simulated propellent storage tank during tank-to-tank cryogen transfer in microgravity.
NPJ Microgravity
June 2024
NASA Glenn, Research Center, Cleveland, OH, USA.
The space exploration from a low earth orbit to a high earth orbit, then to Moon, Mars, and possibly asteroids and moons of other planets is one of the biggest challenges for scientists and engineers for the new millennium. The enabling of in-space cryogenic rocket engines and the Lower-Earth-Orbit (LEO) cryogenic fuel depots for these future manned and robotic space exploration missions begins with the technology development of advanced cryogenic thermal-fluid management systems for the propellant transfer line and storage tank system. One of the key thermal-fluid management operations is the chilldown and filling of the propellant storage tank in space.
View Article and Find Full Text PDFPharmaceutical Nanoparticles Formation and Their Physico-Chemical and Biomedical Properties.
Pharmaceuticals (Basel)
May 2024
Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow 119991, Russia.
The use of medicinal substances in nanosized forms (nanoforms, nanoparticles) allows the therapeutic effectiveness of pharmaceutical preparations to be increased due to several factors: (1) the high specific surface area of nanomaterials, and (2) the high concentration of surface-active centers interacting with biological objects. In the case of drug nanoforms, even low concentrations of a bioactive substance can have a significant therapeutic effect on living organisms. These effects allow pharmacists to use lower doses of active components, consequently lowering the toxic side effects of pharmaceutical nanoform preparations.
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