AI Article Synopsis
- Moderate wine consumption may have health benefits due to bioactive polyphenols that affect gut microbiota.
- The metabolism of these compounds is influenced by gut bacteria, which can encourage beneficial bacteria while inhibiting harmful ones.
- Understanding the interactions between wine polyphenols and gut bacteria is crucial to linking diet with specific health outcomes, and advanced analytical methods can enhance this research.
Article Abstract
Moderate consumption of wine seems to produce positive health effects derived from the occurrence of bioactive polyphenols. The gut microbiota is involved in the metabolism of phenolic compounds, and these compounds and/or their metabolites may modulate gut microbiota through the stimulation of the growth of beneficial bacteria and the inhibition of pathogenic bacteria. The characterization of bacterial metabolites derived from polyphenols is essential in order to understand their effects, including microbial modulation, and therefore to associate dietary intake with particular health effects. This review aims to summarize the current information about the two-way "wine polyphenols-gut microbiota" interaction, from a perspective based on the experimental and analytical designs used. The availability of advanced methods for monitoring bacterial communities, along with the combination of in vitro and in vivo models, could help to assess the metabolism of polyphenols in the human body and to monitor total bacterial communities, and, therefore, to elucidate the implications of diet on the modulation of microbiota for delivering health benefits.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665564 | PMC |
| http://dx.doi.org/10.3390/antiox4010001 | DOI Listing |
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