Answer questions and earn CME/CNE Sexual concerns are prevalent in women with cancer or cancer history and are a factor in patient decision making about cancer treatment and risk-reduction options. Physical examination of the female cancer patient with sexual concerns, regardless of the type or site of her cancer, is an essential and early component of a comprehensive evaluation and effective treatment plan. Specialized practices are emerging that focus specifically on evaluation and treatment of women with cancer and sexual function problems. As part of a specialized evaluation, oncologists and their patients should expect a thorough physical examination to identify or rule out physical causes of sexual problems or dysfunction. This review provides oncology professionals with a description of the physical examination of the female cancer patient with sexual function concerns. This description aims to inform anticipatory guidance for the patient and to assist in interpreting specialists' findings and recommendations. In centers or regions where specialized care is not yet available, this review can also be used by oncology practices to educate and support health care providers interested in expanding their practices to treat women with cancer and sexual function concerns. CA Cancer J Clin 2016;66:241-263. © 2016 American Cancer Society.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860140PMC
http://dx.doi.org/10.3322/caac.21337DOI Listing

Publication Analysis

Top Keywords

physical examination
16
examination female
12
female cancer
12
cancer patient
12
patient sexual
12
sexual concerns
12
women cancer
12
sexual function
12
cancer
11
oncologists patients
8

Similar Publications

Background: Both novel anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugates (ADCs) and pertuzumab and trastuzumab (HP) combined with chemotherapy(C) regimens are the choice of treatment for HER2 positive metastatic breast cancer (MBC) after tyrosine kinase inhibitors (TKIs). Our team's previous research has shown significant therapeutic effects of novel anti-HER2 ADCs in patients with TKIs treatment failure. Unfortunately, there is currently no data available to compare novel anti-HER2 ADCs with HP combined with chemotherapy regimens.

View Article and Find Full Text PDF

Biomarkers.

Alzheimers Dement

December 2024

National Institute of Mental Health, Neurology and Neurosurgery, Budapest, Hungary.

Background: Growing evidence suggests that the imbalance between excitability and inhibitory neural activity is a key aspect of cognitive decline. Subclinical epileptiform activity (SEA) has been indicated as a marker of increased cortical excitability. While SEA is considered as a benign EEG sign in the elderly population, recent studies demonstrated its role in the progression of Alzheimer's disease.

View Article and Find Full Text PDF

Biomarkers.

Alzheimers Dement

December 2024

Wisconsin Alzheimer's Disease Research Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.

Background: Physical activity (PA) and peripheral insulin resistance are two promising targets for delaying the onset of cognitive impairment in preclinical Alzheimer's disease (AD). Understanding how these factors interact and whether their influence on cognitive outcomes is sex-dependent may be crucial for designing effective lifestyle interventions to protect aging brain health. This study examines whether PA and sex modify the relationship between diabetic-level peripheral insulin resistance and cognitive function in a sample enriched with risk for AD.

View Article and Find Full Text PDF

Background: Control of breathing is known to be adversely affected by cognitive impairment, often associated with sleep apnea or disordered breathing during sleep in MCI/AD. The origin of this disorder is thought to be in the dysfunction of the respiratory control centers of the brainstem or in the impaired afferent signaling from cortical regions. Continuous breathing data were collected in a multi-center study in Los Angeles (USC), Kansas City (KUMC) and Dallas (UT-SWMC), and used to compute respiratory rate variability (RRV) to test the hypothesis that voluntary control of breathing is impaired in MCI and mild AD patients relative to cognitively normal controls, and whether this impairment is more severe in mild AD than MCI patients.

View Article and Find Full Text PDF

Biomarkers.

Alzheimers Dement

December 2024

Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.

Background: Factors contributing to cognitive decline in adults include vascular risk factors (hypertension, hyperlipidemia, diabetes), lower education, age, Apolipoprotein E4(ApoE4) and cerebral hypoperfusion. The interplay between aging and vascular processes disrupts cerebral hemodynamics, heightening the risk of cognitive impairment and neurological disorders. Similarly, ApoE4 gene increases the risk of vascular-related cognitive impairment and small vessel disease.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!