Insulin detemir is commonly used in obese patients with diabetes mellitus as it is considered hepatoselective and causes less weight gain. We describe a relative lack of effectiveness of detemir in patients with significant NAFLD and hypertriglyceridemia, compared to isophane insulin. This may affect how such patients are managed with insulin.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706392PMC
http://dx.doi.org/10.1002/ccr3.458DOI Listing

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