Objectives: To determine the concordance between falls recorded using an investigational fall detection device and falls reported by nursing staff in a nursing home.
Design: Six-month prospective study.
Setting: Hebrew SeniorLife nursing home units in Boston, Massachusetts.
Participants: Nursing home residents with a documented history of at least one fall within 12 months before consent (N = 62, mean age 86.2 ± 8.1, 66% female).
Intervention: Subjects continuously wore an automated falls detection device on a pendant around their neck. The device contained triaxial accelerometers set to detect a rapid change in position that was interpreted as a fall.
Measurements: Healthcare staff reported daily falls, defined as unexpected events in which residents were found on the floor, and the number of these falls was compared with the number of falls recorded according to the device.
Results: Seven of 37 residents whom nursing staff found on the floor had a fall recorded according to the device (19%). The device did not identify any of the clinical fall events in 23 of the 37 fallers (62%). The device detected 17 of 89 total falls that nursing staff recorded (sensitivity 19%) within an 8-hour time window. Of 128 fall events that the device recorded, 17 were concordant with nursing reports (13%) within an 8-hour time window, and 111 (87%) were false positives.
Conclusion: There is poor concordance between falls recorded using the investigational fall detection device and falls to the floor that nursing home staff report.
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http://dx.doi.org/10.1111/jgs.13708 | DOI Listing |
PLoS One
January 2025
Faculty of Engineering (FOE), Multimedia University (MMU), Cyberjaya, Selangor, Malaysia.
Cancer and its diverse variations pose one of the most significant threats to human health and well-being. One of the most aggressive forms is blood cancer, originating from bone marrow cells and disrupting the production of normal blood cells. The incidence of blood cancer is steadily increasing, driven by both genetic and environmental factors.
View Article and Find Full Text PDFJ Ophthalmic Inflamm Infect
January 2025
Ocular Inflammatory Disease Center, UCLA Jules Stein Eye Institute, Los Angeles, USA.
Purpose: To validate automated counts of presumed anterior chamber (AC) cells in eyes with histories of uveitis involving the anterior segment using swept-source (SS) anterior segment optical coherence tomography (AS-OCT) against manual counts and compare automated counts against Standardized Uveitis Nomenclature (SUN) criteria.
Methods: Eyes were imaged with the ANTERION SS AS-OCT device (Heidelberg Engineering). A fully automated custom algorithm quantified the number of hyper-reflective foci (HRF) in line-scan images.
Neuro Oncol
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Department of Neurological Surgery, Mayo Clinic, Rochester, MN, USA.
Cerebrospinal fluid (CSF) has emerged as a valuable liquid biopsy source for glioma biomarker discovery and validation. CSF produced within the ventricles circulates through the subarachnoid space, where the composition of glioma-derived analytes is influenced by the proximity and anatomical location of sampling relative to tumor, in addition to underlying tumor biology. The substantial gradients observed between lumbar and intracranial CSF compartments for tumor-derived analytes underscore the importance of sampling site selection.
View Article and Find Full Text PDFJ Anal Toxicol
December 2024
Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL.
Novel psychoactive substances (NPS) have historically been difficult compounds to analyze in forensic toxicology. The identification, detection and quantitation of these analytes and their metabolites has been difficult due to their rapid emergence, short life span and various potencies. Advancements in analytical instrumentation are fundamental to mitigating these NPS challenges by providing reliable identification and sensitivity.
View Article and Find Full Text PDFBackground: With global dementia prevalence estimated to reach 139 million by 2050, early detection of dementia-causing diseases is crucial for promoting preventative interventions. Wearable technologies have the potential to detect early signs; however, they need to be acceptable amongst users. We explored user's perspectives on the acceptability of wearable devices.
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