Background: Of the proposed algorithms that provide guidance for in-field termination of resuscitation (TOR) decisions, the guidelines for cardiopulmonary resuscitation (CPR) refer to the basic and advanced life support (ALS)-TOR rules. To assess the potential consequences of implementation of the ALS-TOR rule, we performed a case-by-case evaluation of our in-field termination decisions and assessed the corresponding recommendations of the ALS-TOR rule.

Methods: Cohort of non-traumatic out-of-hospital cardiac arrest (OHCA)-patients who were resuscitated by the ALS-practising emergency medical service (EMS) in the Nijmegen area (2008-2011). The ALS-TOR rule recommends termination in case all following criteria are met: unwitnessed arrest, no bystander CPR, no shock delivery, no return of spontaneous circulation (ROSC).

Results: Of the 598 cases reviewed, resuscitative efforts were terminated in the field in 46% and 15% survived to discharge. The ALS-TOR rule would have recommended in-field termination in only 6% of patients, due to high percentages of witnessed arrests (73%) and bystander CPR (54%). In current practice, absence of ROSC was the most important determinant of termination [aOR 35.6 (95% CI 18.3-69.3)]. Weaker associations were found for: unwitnessed and non-public arrests, non-shockable initial rhythms and longer EMS-response times.

Conclusion: While designed to optimise hospital transportations, application of the ALS-TOR rule would almost double our hospital transportation rate to over 90% of OHCA-cases due to the favourable arrest circumstances in our region. Prior to implementation of the ALS-TOR rule, local evaluation of the potential consequences for the efficiency of triage is to be recommended and initiatives to improve field-triage for ALS-based EMS-systems are eagerly awaited.

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http://dx.doi.org/10.1016/j.resuscitation.2015.12.014DOI Listing

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Article Synopsis
  • The study's aim was to create a scoring model to identify individuals who could still benefit from resuscitation efforts after out-of-hospital cardiac arrest, despite meeting termination of resuscitation rules.
  • Researchers analyzed data from the All-Japan Utstein Registry between 2010 and 2019, focusing on patients who met basic and advanced life support termination rules and used statistical methods to find factors linked to favorable neurological outcomes.
  • The resulting scoring model, particularly for those under the basic life support category, utilized age, cardiac rhythm, and transport time to predict outcomes, revealing that patients with higher scores had a slightly increased probability of favorable outcomes, although most scored below the threshold needed for a meaningful chance.
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Termination of resuscitation in out-of-hospital cardiac arrest in women and men: An ESCAPE-NET project.

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Amsterdam UMC, Academic Medical Centre, University of Amsterdam, Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands; Netherlands Heart Institute, Utrecht, The Netherlands. Electronic address:

Aim: Women have less favorable resuscitation characteristics than men. We investigated whether the Advanced Life Support Termination of Resuscitation rule (ALS-TOR) performs equally in women and men. Additionally, we studied whether adding or removing criteria from the ALS-TOR improved classification into survivors and non-survivors.

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Department of Emergency Medicine, Osaka Medical and Pharmaceutical University, Osaka, Japan; Department of Pediatrics, Osaka Medical and Pharmaceutical University, Osaka, Japan; Division of Patient Safety, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan. Electronic address:

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Cost-effectiveness analysis of termination-of-resuscitation rules for patients with out-of-hospital cardiac arrest.

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Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 1130033, Japan.

Aim: To evaluate the cost-effectiveness of practices with and without termination-of-resuscitation (TOR) rules for out-of-hospital cardiac arrest (OHCA), using an analytic model based on a nationwide population-based registry in Japan.

Methods: A combined model using a decision tree and Markov model was developed to compare costs and treatment effectiveness of three scenarios: basic life support (BLS) TOR rules (BLS-rule scenario), advanced life support (ALS) TOR rules (ALS-rule scenario), and no TOR rules (No-rule scenario). A nationwide population-based OHCA registry from January 1 to December 31, 2019 and published data were used.

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