Delirium is a common complication among hospitalized elderly individuals. Systemic analgesics are known precipitating factors for delirium. However, the risk from topical pain agents is not well documented. We report a case of a woman who developed delirium after the application of a lidocaine patch. Although lidocaine patches are generally perceived as safe, clinicians should be aware of delirium as a potential adverse effect, particularly in older patients. This report also highlights the role of a systematic approach of staff education, use of a standardized protocol, and interdisciplinary communication in the identification and management of delirium in acute rehabilitation facilities.
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http://dx.doi.org/10.1016/j.pmrj.2015.12.006 | DOI Listing |
Radiol Oncol
January 2025
1Clinical Department of Anaesthesiology and Intensive Care Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Background: Chronic postoperative pain is the most common postoperative complication that impairs quality of life. Postoperative pain gradually develops into neuropathic pain. Multimodal analgesia targets multiple points in the pain pathway and influences the mechanisms of pain chronification.
View Article and Find Full Text PDFJ Pain Res
December 2024
Department of Pain Management, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, People's Republic of China.
Objective: The current landscape is characterized by a dearth of effective, safe, simple, and noninvasive methods for preventing pain following craniotomy. This clinical trial seeks to evaluate the efficacy profile of preemptive application of a topical 5% lidocaine patch in alleviating post-craniotomy pain.
Methods: This was a multi-centric, prospective randomized placebo-controlled triple-blind clinical trial.
Mol Pharm
January 2025
School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
J Diabetes Metab Disord
December 2024
Anesthesiology Department, State University of Campinas, Campinas, Brazil.
Front Pharmacol
October 2024
Department of Pain Medicine, The First Affiliated Hospital of Soochow University, Suzhou, China.
Background: With an aging population, knee arthroplasty is increasingly common; however, chronic postsurgical pain (CPSP) affects up to 30% of patients. This study aims to evaluate the efficacy of 5% lidocaine-medicated plaster (LP5) in preventing CPSP among patients undergoing knee arthroplasty.
Methods: This is a dual-center, randomized, double-blind, placebo-controlled trial involving 128 adult patients scheduled for knee arthroplasty.
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