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Towards evaluating and building versatile large language models for medicine.
NPJ Digit Med
January 2025
Shanghai Jiao Tong University, Shanghai, China.
In this study, we present MedS-Bench, a comprehensive benchmark to evaluate large language models (LLMs) in clinical contexts, MedS-Bench, spanning 11 high-level clinical tasks. We evaluate nine leading LLMs, e.g.
View Article and Find Full Text PDFPublic Understanding and Expectations of Digital Health Evidence Generation: Focus Group Study.
JMIR Form Res
January 2025
Institute of Health Informatics, University College London, 222 Euston Road, London, NW1 2DA, United Kingdom, 44 07742966769.
Background: The rapid proliferation of health apps has not been matched by a comparable growth in scientific evaluations of their effectiveness, particularly for apps available to the public. This gap has prompted ongoing debate about the types of evidence necessary to validate health apps, especially as the perceived risk level varies from wellness tools to diagnostic aids. The perspectives of the general public, who are direct stakeholders, are notably underrepresented in discussions on digital health evidence generation.
View Article and Find Full Text PDFSimultaneous determination of busulfan, fludarabine, phenytoin, and posaconazole in plasma from patients undergoing hematopoietic stem cell transplantation.
J Pharm Biomed Anal
January 2025
Department of Pharmacy, Hebei Children's Hospital, Shijiazhuang, Hebei 050031, China. Electronic address:
A simple, fast, sample-saving, and sensitive liquid chromatography-tandem mass spectrometry method was established with a linear range adjusted by in-source collision-induced dissociation. Notably, this could simultaneously determine busulfan, fludarabine, phenytoin, and posaconazole in plasma from children, each having unique physical and chemical properties. The procedure necessitated only 20 μL of plasma and involved a simple protein precipitation process.
View Article and Find Full Text PDFDevelopment of mobile educational applications designed for nurses: A narrative review.
Nurse Educ Today
January 2025
School of Nursing and Midwifery, Deakin University, Burwood, Victoria 3125, Australia; Centre for Quality and Patient Safety Research in the Institute for Health Transformation, Victoria, Australia.
Objective: To identify and synthesise existing literature about the use of mobile educational applications (apps) designed to enhance the learning experience of nurses and midwives.
Design: A narrative review using a systematic, structured and comprehensive search of the literature.
Data Sources: Medline Complete (EBSCO), CINAHL (EBSCO), ERIC (EBSCO) and Embase (OVID) electronic databases.
Genetic and species rearrangements in microbial consortia impact biodegradation potential.
ISME J
January 2025
Universidad Pablo de Olavide, Centro Andaluz de Biología del Desarrollo/ Consejo Superior de Investigaciones Científicas/ Junta de Andalucía, Seville, Spain.
Genomic reorganisation between species and horizontal gene transfer have been considered the most important mechanism of biological adaptation under selective pressure. Still, the impact of mobile genes in microbial ecology is far from being completely understood. Here we present the collection and characterisation of microbial consortia enriched from environments contaminated with emerging pollutants, such as non-steroidal anti-inflammatory drugs.
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