Objective: This study aimed to investigate the correlation between strain and elasticity of the common carotid artery (CCA) by ultrasonography and evaluate its clinical significance in patients with diabetic nephropathy (DN).
Methods: A total of 68 DN patients and 54 healthy subjects were randomly recruited from the Ultrasound Department from April 2014 to March 2015. The maximum of circumferential strain (CSmax), maximum of circumferential strain rate (CSRmax), compliance coefficient (CC) and stiffness index (β) of the CCA were determined by ultrasonography in all the patients, and correlation analysis was performed.
Results: The CC, CSmax and CSRmax in DN group were significantly lower than in healthy controls (P<0.05), but β was markedly higher than in control group (P<0.05). There was a significantly positive correlation of CSmax and CSRmax with CC and a negative correlation with β in both control group and DN group.
Conclusion: There is significant correlation between strain and elastic of the CCA. CSmax and CSRmax may be used to reflect the mechanical characteristics of CCA.
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