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| http://dx.doi.org/10.1177/1756283X15615309 | DOI Listing |
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Scale-up of CHO cell cultures: from 96-well-microtiter plates to stirred tank reactors across three orders of magnitude.
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Biochemical Engineering (AVT.BioVT), RWTH Aachen University, Aachen, Germany.
Background: For process development in mammalian cell cultivations, scale-up approaches are essential. A lot of studies concern the scale transfer between different-sized stirred tank reactors. However, process development usually starts in even smaller cultivation vessels like microtiter plates or shake flasks.
View Article and Find Full Text PDFReconstruction of reverberant sound fields over large spatial domains.
J Acoust Soc Am
January 2025
Acoustic Technology, Department of Electrical & Photonics Engineering, Technical University of Denmark, Kongens Lyngby, Denmark.
Characterising acoustic fields in rooms is challenging due to the complexity of data acquisition. Sound field reconstruction methods aim at predicting the acoustic quantities at positions where no data are available, incorporating generalisable physical priors of the sound in a room. This study introduces a model that exploits the general time structure of the room impulse response, where a wave-based expansion addresses the direct sound and early reflections, localising their apparent origin, and kernel methods are applied to the late part.
View Article and Find Full Text PDFHand Rejuvenation Using Autologous Fat Grafting: A Systematic Review of Recommended Doses, Complications, and Patient Satisfaction.
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Division of Plastic Surgery, Department of Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Introduction: Hand rejuvenation addresses aging-related changes such as subcutaneous fat loss, skin degradation, and photodamage. Autologous fat transfer (AFT) has emerged as a promising treatment, offering durable volume augmentation and regenerative effects. This study aims to systematically review the evidence on the techniques, outcomes, and complications of AFT for hand rejuvenation.
View Article and Find Full Text PDFBlarcamesine for the treatment of Early Alzheimer's Disease: Results from the ANAVEX2-73-AD-004 Phase IIB/III trial.
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January 2025
Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA. Electronic address:
Background: There are no approved oral disease-modifying treatments for Alzheimer's disease (AD).
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Intensifying Stabilization and Dissolution Capacity of Polyacrylamide Emulsion Drag Reducers Using a pH-Switchable Four-Tailed Ionic Liquid Surfactant.
Langmuir
January 2025
National Key Laboratory of Oil and Gas Reservoir Geology and Exploitation, Southwest Petroleum University, Chengdu 610500, P. R. China.
To balance the stability and dissolution of polyacrylamide (PAM), emulsion drag reducers dominate the successful operation of volumetric fracturing. Herein, a pH-switchable four-tailed ionic liquid surfactant (OA/Cyclen) is synthesized by oleic acid (OA) and 1,4,7,10-tetraazacyclododecane (Cyclen). The four-tailed structure of OA/Cyclen enhances the stability of the emulsion polymerization reactor and supplies enough switchable sites for triggering the intensified release of the PAM emulsion.
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