Objective: To study the chemical constituents of Plantago asiatica seeds.
Methods: The constituents were isolated from the seeds of Plantago asiatica by column chromatography over silica gel, MCI gel, macroporous resin HP-20, Sephadex LH-20, Polyamide and by preparative HPLC. Their structures were elucidated by analysis of physical and chemical properties and spectral data.
Results: Five compounds were isolated and their structures were identified as acteoside (1), isoacteoside (2), decaffeoylacteoside (3), tetradecanoic acid (4), and bis (2-ethythexyl) benzene-1,2-dicarboxylate (5).
Conclusion: Compound 5 is isolated from Plantaginaceae for the first time. Compounds 3 and 4 are firstly characterized in Plantago asiatica.
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