Analysis of illicit drugs by direct ablation of solid samples.

Eur J Mass Spectrom (Chichester)

Grupo de Espectroscopia Molecular (GEM), Edificio Quifima. Laboratorios de Espectroscopia y Bioespectroscopia, Unidad Asociada CSIC, Parque Científico Uva, Universidad de Valladolid, Paseo Belén 5, ES-47011, Valladolid, Spain.

Published: February 2016

Analysis of illicit drugs arises as an important field of work given the high social impacts presented by drugs in the modern society. Direct laser ablation of solid compounds allows their analysis without sampling or preparation procedures. For that purpose, an experimental set-up that combines laser ablation with time-of- flight mass spectrometry has been constructed very recently to perform studies on the mass spectra of such drugs as 3,4-methylenedioxy-N-methylamphetamine, commonly known as MDMA or ecstasy. Analysis of the observed fragmentation pattern in mass spectra may elucidate the ablation-induced photofragmentation phenomena produced, which differ from those previously observed with conventional ionization methods.

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http://dx.doi.org/10.1255/ejms.1399DOI Listing

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