In vitro antimicrobial susceptibility of Alloscardovia omnicolens and molecular mechanisms of acquired resistance.

Diagn Microbiol Infect Dis

CHU de Caen, Service de Microbiologie, F-14033 Caen, France; Université de Caen Basse-Normandie, EA4655 (équipe "Antibiorésistance"), F-14032 Caen, France; CNR de la Résistance aux Antibiotiques, Laboratoire Associé "Entérocoques et résistances particulières des bactéries à Gram positif", F-14033 Caen, France. Electronic address:

Published: March 2016

All the 31 isolates of Alloscardovia omnicolens exhibited low MICs for β-lactams, glycopeptides, linezolid, tetracyclines, and cotrimoxazole. One strain showed MICs ≥256μg/mL for both erythromycin and clindamycin with a single point mutation in 23S rRNA. One strain likely had acquired fluoroquinolone resistance associated with a unique mutation in ParC.

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http://dx.doi.org/10.1016/j.diagmicrobio.2015.08.009DOI Listing

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