Objective: To investigate the steroidal glycoside constituents of Solanum cumingii.

Methods: The compounds were isolated by silica gel, Sephadex LH-20, RP-C18 column and Pre-HPLC chromatography. Their structures were identified by ESI-MS and NMR.

Results: Six known compounds including torvoside K (1), torvoside J (2), torvoside L (3), khasianine (4), aculeatiside A (5) and solamargine (6) were isolated from Solanum cumingii.

Conclusion: All compounds are isolated from Solanum cumingii for the first time.

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