AI Article Synopsis

  • The study focuses on patients diagnosed with multiple myeloma, aiming to understand its correlation with mortality rates.
  • Conducted at a medical school, the research analyzed patient data from 2006 to 2010, revealing a median age of 58.5 years, high rates of anemia (87%) and significant creatinine levels (19%).
  • Findings indicate a five-year survival rate of 74.6%, with Durie-Salmon staging showing a significant link to patient outcomes, while other staging systems did not have a notable impact on survival rates.

Article Abstract

Objective: To present a descriptive analysis of patients diagnosed with multiple myeloma, correlating it with mortality.

Methods: A retrospective study that analyzed consecutive patients diagnosed with multiple myeloma under follow-up at the Faculdade de Medicina do ABC from 2006 to 2010.

Results: The median age was 58.5 years. Anemia was observed upon diagnosis in 87% of patients, hypercalcemia in 38%, and creatinine levels higher than 2 mg/dL in 19%. M protein was detected in 85.7%. The five-year survival rate was 74.6%. Multivariate analysis showed statistical significance for Durie-Salmon staging (p = 0.037). The International Staging System and immunoglobulin type did not correlate significantly with survival of the group.

Conclusion: This set of cases from a tertiary public healthcare service reflect the approach of multiple myeloma in a predominantly young population with advanced clinical staging, with results comparable to those of the literature.

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Source
http://dx.doi.org/10.1590/S1679-45082011AO2006DOI Listing

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