AIDS and the pinball wizard.

Br J Hosp Med

Published: September 1989

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Robust regression for optimal individualized treatment rules.

Stat Med

May 2019

Department of Statistics, North Carolina State University, Raleigh, North Carolina.

Because different patients may respond quite differently to the same drug or treatment, there is an increasing interest in discovering individualized treatment rules. In particular, there is an emerging need to find optimal individualized treatment rules, which would lead to the "best" clinical outcome. In this paper, we propose a new class of loss functions and estimators based on robust regression to estimate the optimal individualized treatment rules.

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