Drug-Related Eyelid Nystagmus: Two Cases of a Rare Clinical Phenomenon Related to Carbamazepine and Derivatives.

Clin Neuropharmacol

*Department of Neurology, University Hospital "12 de Octubre"; †Fundación de Investigación "i+12"; ‡Department of Neurology, Hospital del Tajo, Aranjuez; §Department of Medicine, Faculty of Medicine, Complutense University; and ∥Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED),Madrid, Spain.

Published: October 2016

Background: Eyelid nystagmus is a rare clinical phenomenon described mostly related to brainstem or cerebellum lesions. The mechanism of this phenomenon is incompletely understood.

Patients And Methods: We report 2 cases of eyelid nystagmus induced by carbamazepine and oxcarbazepine intoxication.

Conclusions: Carbamazepine and derivatives may induce eyelid nystagmus in the setting of acute intoxication. To the best of our knowledge, these are the first cases of drug-related eyelid nystagmus.

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Source
http://dx.doi.org/10.1097/WNF.0000000000000125DOI Listing

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