The disease, endometriosis, occurs in very varying forms and degrees of severity. Classification of the disease is therefore important. Acosta's classification was previously most frequently employed. A more recent system of classification (R-AFS) proposed by the American Fertility Society is employed here. This system is based on scoring of various elements of endometriosis. Employing this system of classification, which is now internationally used, a more differentiated description of the disease is obtained and also improved assessment of bilateral involvement. Various therapeutic possibilities are reviewed including the question of whether minimal-mild endometriosis should be treated at all. Recent therapeutic possibilities for endometriosis with laser surgery and "medical oophorectomy" employing GnRH analogues are discussed and also employment of in vitro fertilization for patients with endometriosis is mentioned. Finally, treatment with danazol and the classical therapeutic agents such as oral contraception, gestagens and surgery are reviewed with the authors' proposals of suitable patients for each form of treatment.
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Curr Drug Targets
January 2025
Chitkara College of Pharmacy, Chitkara University, Punjab, 140401, India.
Acne vulgaris is the 8th most commonly prevailing skin disorder worldwide. Its pervasiveness has been predominant in juveniles, especially males, during adolescence and in females during adulthood. The lifestyle and nutrition adopted have been significantly reported to impact the occurrence and frequency of acne.
View Article and Find Full Text PDFNano Lett
January 2025
State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing 100084, China.
Ultrafine droplets are crucial in materials processing and nanotechnology, with applications in nanoparticle preparation, water evaporation, nanodrug delivery, nanocoating, among numerous others. While the potential of turbulent gas flow to enhance liquid breakup is acknowledged, constructing turbulence-driven atomizers for ultrafine droplets remains challenging. Herein, we report the innovation of grid-turbulence atomization (GTA), which employs a rotating mesh to deliver liquid and an air knife to spray ultrafine droplets.
View Article and Find Full Text PDFComput Methods Biomech Biomed Engin
January 2025
Department of Mathematics, National Institute of Technology Uttarakhand, Srinagar, India.
As humans age, they experience deformity and a decrease in their bone strength, such brittleness in the bones ultimately lead to bone fracture. Magnetic field exposure combined with physical exercise may be useful in mitigating age-related bone loss by improving the canalicular fluid motion within the bone's lacuno-canalicular system (LCS). Nevertheless, an adequate amount of fluid induced shear stress is necessary for the bone mechano-transduction and solute transport in the case of brittle bone diseases.
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January 2025
Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China.
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View Article and Find Full Text PDFJACS Au
January 2025
College of Chemical and Biological Engineering, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
The total oxidation of -hexane, a hazardous volatile organic compound (VOC) emitted by the pharmaceutical industry, presents a significant environmental challenge due to limited catalyst activity at low temperatures and poor stability at high temperatures. Here, we present a novel approach that overcomes these limitations by employing single-atom Ag/MnO catalysts coupled with nonthermal plasma (NTP). This strategy achieves exceptional performance in -hexane oxidation at low temperatures, demonstrating 96.
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