Protection by recombinant human superoxide dismutase in lethal rat endotoxemia.

Prog Clin Biol Res

Department of Pharmacology, Grünenthal GmbH, Aachen, FRGermany.

Published: October 1989

In summary as mechanism of the overall protective effect of r-HSOD in lethal rat endotoxemia, inhibition of hemoconcentration, a tendency of a decreased leukocyte activation and attenuation of consumption coagulopathy could be established.

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