Three methods of transit dosimetry using Electronic Portal Imaging Devices (EPIDs) were investigated for use in routine in-vivo dosimetry for cranial stereotactic radiosurgery and radiotherapy. The approaches examined were (a) A full Monte Carlo (MC) simulation of radiation transport through the linear accelerator and patient; (b) Calculation of the expected fluence by a treatment planning system (TPS); (c) Point doses calculated along the central axis compared to doses calculated using parameters acquired using the EPID. A dosimetric comparison of each of the three methods predicted doses at the imager plane to within ±5% and a gamma comparison for the MC and TPS based approaches showed good agreement for a range of dose and distance to agreement criteria. The MC technique was most time consuming, followed by the TPS calculation with the point dose calculation significantly quicker than the other methods.
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http://dx.doi.org/10.1016/j.ejmp.2015.12.001 | DOI Listing |
J Med Internet Res
January 2025
Institute for Better Health, Trillium Health Partners, Mississauga, ON, Canada.
Background: Patient portals, or secure websites linked to electronic medical records, have emerged as tools to provide patients with timely access to their health information. To support the potential benefits of patient portals such as improved engagement in health care, it is essential to understand how patients and caregivers experience these portals.
Objective: This study aimed to explore patient and caregiver experiences, facilitators, and barriers to accessing and using a patient portal called MyChart during the initial stages of its implementation.
EClinicalMedicine
February 2025
Faculty of Medicine, University of Queensland, Australia.
Background: Small Intestinal Bacterial Overgrowth (SIBO) has been implicated in the pathophysiology of chronic liver disease (CLD). We conducted a systematic review and meta-analysis to assess and compare the prevalence of SIBO among CLD patients (with and without with complications of end stage liver disease) and healthy controls.
Methods: Electronic databases were searched from inception up to July-2024 for case-control studies reporting SIBO in CLD.
J Gen Intern Med
January 2025
Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Objective: The aim of this study was to assess changes in the accessibility and utilization of electronic health record patient portals in recent years, focusing on whether these changes occurred equitably across different racial, ethnic, and socioeconomic groups.
Materials And Methods: The study utilized nationally representative samples from the 2019 and 2022 Health Information National Trends Surveys. A difference-in-differences design was used to determine if increases in access and utilization occurred equally for all segments of the population.
J Mol Biol
February 2025
University Côte d'Azur, INSERM, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, "Laboratory of Excellence (LABEX) Distalz", Valbonne, France. Electronic address:
Transcription is a key cell process that consists of synthesizing several copies of RNA from a gene DNA sequence. This process is highly regulated and closely linked to the ability of transcription factors to bind specifically to DNA. TFinder is an easy-to-use Python web portal allowing the identification of Individual Motifs (IM) such as Transcription Factor Binding Sites (TFBS).
View Article and Find Full Text PDFJ Hazard Mater
January 2025
Laboratory of Nuclear Energy Chemistry, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China; School of Nuclear Science and Engineering, and Key Laboratory of Nuclear Power Systems and Equipment/Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address:
In this work, we use a well-defined water-soluble macrocyclic molecule cucurbit[5]uril (CB5) to modify 2D TiCT MXene and assemble a novel high-performance adsorbent CB5-TiCT for Sr ion by density functional theory and experimental methods. The structural stabilities of two distinct types of CB5-TiCT (T = F, O and OH) complexes, i.e.
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