Anticancer Teamwork: Cross-Presenting Dendritic Cells Collaborate with Therapeutic Monoclonal Antibodies.

Cancer Discov

Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, Toronto, Canada. Department of Oncology and Ludwig Center for Cancer Research, University of Lausanne, Switzerland.

Published: January 2016

Cross-presentation of tumor antigens represents a key pathway in antitumor immune responses that can be exploited to synergize not only with the already prominent "checkpoint blockade," but also with newer attempts to use T-cell stimulatory monoclonal antibodies in immunotherapy.

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Source
http://dx.doi.org/10.1158/2159-8290.CD-15-1366DOI Listing

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