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Nd: YAP Laser in the Elimination of Endodontic Nickel-Titanium Files Fractured in Rooted Canals (Part 1: Teeth With Minimal Root Curvature).
Cureus
December 2024
Department of Dental Sciences, Faculty of Medicine, University of Liege, Liege, BEL.
Background Fracture of nickel-titanium (Ni-Ti) instruments in root canals is commonly associated with compromised outcomes in endodontic treatment. There is no single, universally accepted approach for managing this complication. The objective of this study is to evaluate the effectiveness of an Nd: YAP laser-assisted protocol in removing fractured Ni-Ti files in teeth with minimal root curvature (less than 15 degrees).
View Article and Find Full Text PDFAssessing Cancer Knowledge in the General Population of Bisha Province, Saudi Arabia: A Cross-Sectional Study.
Cureus
December 2024
Department of Surgery, College of Medicine, University of Bisha, Bisha, SAU.
Background Cancer is a major cause of morbidity and mortality worldwide. It is anticipated that the number of new cases in Saudi Arabia will increase yearly as a result of significant changes in lifestyle and population development. There is little to no information or studies concerning cancer awareness or knowledge among the residents of Bisha Province.
View Article and Find Full Text PDFDMR040, a potential antifungal compound.
J Antibiot (Tokyo)
January 2025
Shanghai Duomirui Biotechnology Ltd., Shanghai, China.
Based on DMR022 [(AEEA-Gly)-AEEA-amphotericin B methyl ester, AEEA is the abbreviation of 8-amino-3,6-dioxaoctanoic acid] and DMR031 [(AEEA)-amphotericin B methyl ester], DMR040 [(AEEA)-amphotericin B methyl ester] was further designed and synthesised. Firstly, DMR040 was assessed for its antifungal activity and haemolytic toxicity with the broth dilution method and sterile defibrinated sheep blood, respectively. The minimal inhibitory concentration (MIC) of DMR040 (2 μg/mL) against Candida albicans ATCC 10231 and ATCC 90028 was reduced by 2 times compared to that of amphotericin B (1 μg/mL).
View Article and Find Full Text PDFIntegrating Dermocosmetic Therapy for Acne: Addressing Severity Levels in Real-Life Experiences.
J Drugs Dermatol
January 2025
Background: Acne is prevalent in approximately 80% of individuals aged 11 to 30 years, with scarring occurring in about 40% of cases. Early and sustained treatment is crucial for preventing acne scarring, regardless of severity.
Objectives: The objective of this study was to evaluate skin tolerability and patient compliance after combining a specific dermatologic routine with pharmacological therapy in patients affected by different degrees of acne.
Use of nicotine products, prescription drug products, and other methods to stop smoking by US adults in the 2022 National Health Interview Survey.
Intern Emerg Med
January 2025
Department of Social and Behavioral Sciences, School of Global Public Health, New York University, New York, NY, USA.
Article Synopsis
- A recent CDC survey analyzed methods used by US adults to stop smoking, showing that around 2.9 million adults successfully quit for at least 6 months in the last year.
- Most successful quitters were younger, educated, male, non-Hispanic White, and commonly used nicotine products, especially e-cigarettes, compared to less popular options like prescription drugs.
- The study highlights that many adults still try to quit smoking without support, suggesting a need for targeted interventions to help those who struggle the most in quitting, using proven methods.
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