AI Article Synopsis
- Nano-TiO2 is used in automobile exhaust systems to reduce harmful nitric oxide (NO) emissions, which also plays a role in vasodilation and swelling in the human body.
- Recent research shows that nano-TiO2 can significantly lower NO production in mouse macrophages, suggesting its potential as a deswelling agent.
- The development of a nano-TiO2 ointment demonstrated similar effects in reducing swelling, highlighting its promise for treating diseases associated with edema.
Article Abstract
Nano-TiO2 is widely applied in the automobile exhaust hose reels as a catalyst to reduce oxynitride emissions, including nitric oxide (NO). In the biomedicine field, NO plays an important role in vasodilation and edema formation in human bodies. However, the deswelling activity of nano-TiO2 has not been reported. Here, we demonstrated that nano-TiO2 can significantly degrade the production of NO in LPS-induced RAW264.7 mouse macrophages. Further study indicated that nano-TiO2 exhibited an effect on vascular permeability inhibition, and prevented carrageenan-induced footpad edema. Therefore, we prepared a nano-TiO2 ointment and observed similar deswelling effects. In conclusion, nano-TiO2 might act as a novel deswelling agent related with its degradation of NO, which will aid in our ability to design effective interventions for edema involved diseases.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272895 | PMC |
| http://dx.doi.org/10.3390/molecules21010057 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
An in vitro evaluation of anti-oxidant properties of novel nano-composite material containing titanium oxide, zinc oxide and green tea extract.
Med J Malaysia
January 2025
Department of Mechanical engineering, IIT Madras.
Introduction: Green tea is a medicinal beverage extracted from the plant Camellia sinensis. Antioxidants that exist naturally can be extracted as pure compounds from their parent materials for nutraceutical and medicinal applications. The present study aims to assess the antioxidant activity of Zinc oxide-titanium dioxide nano-composites (ZnO-TiO2 NCs) containing green tea extract.
View Article and Find Full Text PDFDegradation of AFB in edible oil by aptamer-modified TiO composite photocatalytic materials: Selective efficiency, degradation mechanism and toxicity.
Food Chem
December 2024
Food Engineering Technology Research Center/Key Laboratory of Henan Province, College of Food Science and Technology, Henan University of Technology, Lianhua Street, Zhengzhou 450001, China. Electronic address:
Most of the excessive aflatoxins in peanut oil are present at lower levels, and few photocatalysts have been reported for degrading low concentrations of aflatoxin B (AFB). This study employed aptamer-modified magnetic graphene oxide/titanium dioxide (MGO/TiO-aptamer) photocatalysts to degrade low concentrations of AFB in peanut oil, thoroughly investigating their selective efficiency, degradation mechanism, and product toxicity. The results indicated that the modification of aptamers on the surface of photocatalytic materials can enhance the selectivity of photocatalysts for AFB in peanut oil.
View Article and Find Full Text PDFA novel skin-like patch based on 3D hydrogel nanocomposite of Polydopamine/TiO nanoparticles and Ag quantum dots accelerates diabetic wound healing compared to stem cell therapy.
J Tissue Viability
December 2024
Institute of Nanoscience & Nanotechnology, Kafrelsheikh University, Kafr ElSheikh, 33516, Egypt; Nile Valley University, Fayoum, 63518 Egypt. Electronic address:
Despite the advances in the development of therapeutic wearable wound-healing patches, lack self-healing properties and strong adhesion to diabetic skin, hindering their effectiveness. We propose a unique, wearable patch made from a 3D organo-hydrogel nanocomposite containing polydopamine, titanium dioxide nanoparticles, and silver quantum dots (PDA-TiO@Ag). The designed patch exhibits ultra-stretchable, exceptional-self-healing, self-adhesive, ensuring conformal contact with the skin even during movement.
View Article and Find Full Text PDFProgress in photocatalytic degradation of industrial organic dye by utilising the silver doped titanium dioxide nanocomposite.
Heliyon
December 2024
Mechanical Engineering Department, Faculty of Engineering, Brawijaya University, MT Haryono167, Malang, 65145, Indonesia.
Industrial organic dyes represent a significant portion of pollutants discharged into the environment, particularly by the textile industry. These compounds pose serious threats to living organisms due to their high toxicity. Various techniques have been explored for the degradation of organic dyes, among which heterogeneous photocatalysis utilising titanium dioxide (TiO) stands out as a promising technology.
View Article and Find Full Text PDFAntibiotic residue detection by novel photoelectrochemical extended-gate field-effect transistor sensor.
J Hazard Mater
December 2024
College of Environmental Science and Engineering, Biomedical Multidisciplinary Innovation Research Institute, Shanghai East Hospital, State Key Laboratory of Pollution Control and Resource Reuse, Tongji University, 1239 Siping Road, Shanghai 200092, China; Shanghai Institute of Pollution Control and Ecological Security, Shanghai 200092, China. Electronic address:
Residual antibiotics in the environment may pose threats to both ecological system and public health, necessitating the development of efficient analytical strategy for monitoring and control. This study proposes a photoelectrochemical extended-gate field-effect transistor (PEGFET) sensor for specific and sensitive detection of kanamycin. The sensor utilizes ITO glass as the extended gate electrode (photoelectrode) and titanium dioxide as the photosensitive material.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!