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Clinical Outcomes and Safety Profiles of Generic Versus Brand-Name Clopidogrel in Patients Following Coronary Artery Stent Placement.
Clin Transl Sci
February 2025
The Cardiovascular Department, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Coronary artery disease remains a significant global health issue and is a leading cause of mortality. Dual antiplatelet therapy, including clopidogrel, is essential for preventing stent thrombosis after coronary artery stenting. This study assessed the comparative efficacy and safety of generic versus brand-name clopidogrel in a large Taiwanese cohort.
View Article and Find Full Text PDFStay in the Game: Comprehensive Approaches to Decrease the Risk of Sports Injuries.
Cureus
December 2024
Physiotherapy and Physical Medicine, University of Dschang, Dschang, CMR.
Recurrent sports injuries present complex challenges that extend beyond the playing field, impacting athletes' physical well-being, mental resilience, and financial stability. This review outlines a comprehensive framework designed to prevent and manage these setbacks, empowering athletes to achieve sustained performance and recovery. This multidimensional issue requires an integrative approach encompassing physical rehabilitation, psychological resilience, and nutritional strategies.
View Article and Find Full Text PDFEthical Dilemmas in Clinical Trials of Innovations in Bubble Continuous Positive Airway Pressure Models in Resource-Limited Neonatal Care.
J Paediatr Child Health
January 2025
Bangalore Medical College and Research Institute, Bengaluru, India.
Background: Bubble Continuous Positive Airway Pressure (bCPAP) has become a crucial intervention in neonatal care, particularly in resource-limited settings where access to advanced respiratory support is scarce. While bCPAP offers a cost-effective solution for neonatal respiratory distress, conducting clinical trials in these settings presents significant ethical challenges. Issues of justice, beneficence, and autonomy arise due to disparities in healthcare infrastructure, complexities surrounding informed consent, and the potential exploitation of vulnerable populations.
View Article and Find Full Text PDFRandomized controlled trial on the efficacy of forest walking compared to urban walking in enhancing mucosal immunity.
Sci Rep
January 2025
Le Verseau Inc., Tokyo, 156-0051, Japan.
Scientific research on forest therapy's preventive medical and mental health effects has advanced, but the need for clear evidence for practical applications remains. We conducted an unblinded randomized controlled trial involving healthy men aged 40-70 to compare the physiological and psychological effects of forest and urban walking. Eighty-four participants were randomly assigned to either the forest or urban group, with 78 completing 90-min walks and analysis.
View Article and Find Full Text PDFCoping after the COVID-19 pandemic: nurses' learning intent and implications for the workforce and education.
Br J Nurs
January 2025
Professor, Department of Nursing, Beaver College of Health Sciences, Appalachian State University, Boone, North Carolina, USA.
Background/aim: Addressing the critical global shortage of nurses requires an understanding of how a global pandemic reshaped nurses' motivations and intentions toward education. This study aimed to describe COVID-19's impact on nurses' intent to pursue additional education.
Method: This descriptive study, based in North Carolina in the USA, used content analysis with an inductive approach to examine the responses of nurses to one open-ended question in a large quantitative workforce survey: how has COVID-19 influenced your plans for future education? Responses were coded with counts and organised into themes and subthemes.
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