Bioprosthetic Aortic Valves (BAVs) do not have the serious limitations of mechanical aortic valves in terms of thrombosis. However, the lifetime of BAVs is too short, often requiring repeated surgeries. The lifetime of BAVs might be improved by using computer simulations of the structural behavior of the leaflets. The goal of this study was to develop a numerical model applicable to the optimization of durability of BAVs. The constitutive equations were derived using biaxial tensile tests. Using a Fung model, stress and strain data were computed from biaxial test data. SolidWorks was used to develop the geometry of the leaflets, and ABAQUS finite element software package was used for finite element calculations. Results showed the model is consistent with experimental observations. Reaction forces computed by the model corresponded with experimental measurements when the biaxial test was simulated. As well, the location of maximum stresses corresponded to the locations of frequent tearing of BAV leaflets. Results suggest that BAV design can be optimized with respect to durability.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1109/EMBC.2015.7319102 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Recurrent endocarditis on restrictive perimembranous septal defect causing aortic insufficiency.
Indian J Thorac Cardiovasc Surg
February 2025
Department of Cardiovascular Surgery, Abderrahmen Mami Pneumology and Phthisiology Hospital, Ariana, Tunisia.
Infective endocarditis (IE) in children is a rare entity which presents a high rate of events during follow-up. Congenital heart disease, i particular ventricular septal defect (VSD), is the main predisposing condition to IE at those ages. The long-term risk of IE is of concern and whose follow-up can be complicated by a relapse of IE and reintervention.
View Article and Find Full Text PDFClinical Presentation and Percutaneous Treatment of Hemolytic Anemia Associated With Paravalvular Leak After TAVR.
JACC Case Rep
January 2025
Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA.
Paravalvular leak (PVL) following transcatheter aortic valve replacement (TAVR) is an established complication, albeit rarely associated with hemolytic anemia. This report details 3 cases of significant hemolytic anemia attributed to TAVR-induced PVL, each with distinct clinical presentations and manifestations. These cases underscore the diverse and occasionally subtle clinical presentation of aortic PVL-associated hemolytic anemia.
View Article and Find Full Text PDFTranscatheter Aortic Valve Replacement in Patients With Interventricular Membranous Septal Aneurysms.
JACC Case Rep
January 2025
Interventional Cardiology Section, Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.
Aneurysms of the interventricular membranous septum are a rare anatomical feature that can be detected incidentally on computed tomography or echocardiography. Such aneurysms can pose challenges in the treatment of patients with aortic valve stenosis. A case series of 2 patients with membranous septal aneurysms treated successfully with current-generation balloon-expandable and self-expanding transcatheter heart valves is presented here.
View Article and Find Full Text PDFSurgical Resected Cardiac Angiosarcoma in a 75-Year-Old Patient With a Mitral Valve Bioprosthesis.
JACC Case Rep
December 2024
Department of Nuclear Medicine, Hospital Clínico San Carlos, Madrid, Spain.
A 75-year-old patient with a history of mitral and aortic valve replacement surgery 7 years ago, presented with progressive dyspnea. Transesophageal echocardiogram showed a mass suggestive of bioprosthetic mitral valve thrombosis. We present the investigation process using imaging, surgical findings, nuclear medicine, and histopathology that result in the diagnosis of cardiac angiosarcoma.
View Article and Find Full Text PDFPapillary Fibroelastoma of Aortic Valve: An Echocardiographic Correlation With Surgery and Anatomopathology.
JACC Case Rep
December 2024
Department of Cardiology, Valdivia Hospital, School of Medicine Austral University, Valdivia, Chile.
This case presents a 69-year-old woman with a previous history of arterial hypertension. A transthoracic echocardiogram was requested in the context of shortness of breath with great exercise. Incidentally, at the aortic valve level, a mobile mass suggestive of papillary fibroelastoma was visualized.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!