AI Article Synopsis

  • Uric acid is a metabolic byproduct of purines that plays a key role in initiating the inflammatory process critical for tissue healing.
  • It acts as a scavenger for oxygen free radicals, helping to protect cells from oxidative damage.
  • Uric acid also aids in mobilizing progenitor endothelial cells and supports the adaptive immune system during the healing process.

Article Abstract

Uric acid, a metabolic product of purines, may exert a role in tissue healing. In this review we will explore its role as an alarm initiating the inflammatory process that is necessary for tissue repair, as a scavenger of oxygen free radicals, as a mobilizer of progenitor endothelial cells and as supporter of adaptive immune system.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755186PMC
http://dx.doi.org/10.1590/S0102-6720201500040018DOI Listing

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