AI Article Synopsis
- Thyroiditis causes temporary high thyroid hormone levels (hyperthyroidism) that can later shift to low levels (hypothyroidism) before recovery.
- A case of painless thyroiditis was observed in a patient with no prior thyroid issues after treatment with Nivolumab.
- The report aims to inform clinicians about this potential side effect of Nivolumab and explore its underlying mechanisms and management options.
Article Abstract
Thyroiditis is characterised by transient hyperthyroidism, followed sometimes by hypothyroidism, and then recovery. We report a case of painless drug-induced thyroiditis-in a patient with no history of any thyroid disorder-treated with Nivolumab (an IgG4 monoclonal antibody against Programmed Death Receptor 1). The purpose of this case report is to increase awareness among clinicians regarding this possible adverse effect from Nivolumab, and discuss the possible pathophysiology and management strategies in such patients.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716348 | PMC |
| http://dx.doi.org/10.1136/bcr-2015-213692 | DOI Listing |
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