AI Article Synopsis
- The study examined the link between stunting during the second year of life and later metabolic syndrome components in young adults in Southern Brazil.
- Researchers analyzed data collected over several years, assessing subjects for height and various metabolic health markers like cholesterol and blood pressure.
- The results indicated that while initial associations were observed between stunting and metabolic syndrome components, these associations disappeared after accounting for confounding factors, suggesting no significant link between childhood stunting and adult metabolic health.
Article Abstract
Background/objectives: The aim of this study was to investigate the association between stunting in the second year of life and metabolic syndrome components in early adulthood among subjects who have been prospectively followed-up since birth, in a city in Southern Brazil.
Subjects/methods: In 1984, we attempted to follow-up the entire cohort; the subjects were examined and their mothers interviewed. Stunting was defined by a length-for-age Z-score 2 s.d. or more below the mean, in accordance with the World Health Organization reference. Between 2004 and 2005, we again tried to follow the entire cohort; during this period the subjects were evaluated for the following metabolic syndrome components: high-density lipoprotein (HDL) cholesterol, triglycerides, random blood glucose, waist circumference and systolic and diastolic blood pressure. Family income at the time of the baby's birth, asset index, mother's education, mother's smoking during pregnancy and duration of breastfeeding were considered possible confounders. Linear regression was used in the unadjusted and adjusted analyses.
Results: Among men, stunting was inversely associated with triglycerides (β=-11.90, confidence interval (CI)=-22.33 to -1.48) and waist circumference (β=-4.29, CI=-5.62 to -2.97), whereas for women stunting was negatively related to HDL-cholesterol (β=-4.50, CI=-6.47 to -2.52), triglycerides (β=-9.61, CI=-17.66 to -1.56) and waist circumference (β=-1.14, CI=-4.22 to -1.02). However, after controlling for confounding variables, these associations vanished.
Conclusions: The findings suggest that stunting in childhood is not associated with metabolic syndrome components in young adults.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858756 | PMC |
| http://dx.doi.org/10.1038/ejcn.2015.220 | DOI Listing |
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