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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770508PMC
http://dx.doi.org/10.4103/1008-682X.168789DOI Listing

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Introduction: Varicocele has a detrimental effect on testicular growth and spermatogenesis, hence the importance of its management. This management remains controversial among Tunisian urologists; diagnostic and therapeutic choices tend to vary from one urologist to another.

Aim: The aim of this survey is to evaluate the practices of Tunisian urologists regarding varicocele management compared to the latest international guidelines.

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There has been much controversy about the true value of varicocele repair for improving fertility and the chances of natural conception. This review summarizes the latest research findings, current professional societies' recommendations, and the conclusions of recent systematic reviews and meta-analyses. The current evidence suggests a positive role for varicocele repair in improving basic sperm parameters and increasing the likelihood of natural pregnancy.

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Article Synopsis
  • A systematic review and meta-analysis was conducted to determine the prevalence of anti-sperm antibodies (ASA) in men with varicocele, a condition linked to male infertility.
  • The study analyzed various tests (MAR assay, immunobead test, ELISA) to compare the frequency of ASA positivity in men with varicocele against control subjects without the condition.
  • Findings revealed that men with varicocele showed significantly higher rates of ASA positivity, suggesting an underlying immunological issue contributing to infertility in these patients.
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  • Non-obstructive azoospermia (NOA) is a prevalent and complex issue with varied treatment options and no definitive guidelines, leading to differing management practices internationally.
  • A comprehensive survey with 336 responses from specialists in 49 countries explored current medical and surgical strategies for NOA, analyzing results against existing guidelines and offering expert recommendations.
  • Key findings included diverse approaches to hormonal therapy, significant variation in sperm retrieval success rates, and differing protocols around varicocele repair and follicle-stimulating hormone cutoff levels for sperm retrieval.
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Background: Varicocele is a common occurrence, particularly among men with primary and secondary infertility. There has been extensive research into the management of varicocele in the context of male infertility.

Methods: This article aims to explore the variations in clinical practice in diagnosing and managing varicoceles in infertile men.

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