We present four cases of transitional cell carcinoma of the transplant ureter (TCCtu). In three cases, localized tumor resection and a variety of reconstructive techniques were possible. Transplant nephrectomy with cystectomy was performed as a secondary treatment in one locally excised case. Transplant nephroureterectomy was performed as primary treatment in one case. The role of oncogenic viruses and genetic fingerprinting to determine the origin of TCCtu are described. Our cases and a systematic literature review illustrate the surgical, nephrological, and oncological challenges of this uncommon but important condition.
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http://dx.doi.org/10.1111/ajt.13533 | DOI Listing |
Cureus
November 2024
Department of Surgery, Rush University Medical Center, Chicago, USA.
Transitional cell carcinoma (TCC) of the urinary tract appears more commonly among the transplant population. The increased incidence of TCC has been primarily associated with the male gender, BK virus (BKV), and smoking. We report a case series and comprehensive review of the literature.
View Article and Find Full Text PDFUrologia
August 2024
Department of Urology and Renal Transplant, S.C.B Medical College & Hospital, Cuttack, Odisha, India.
J Cardiothorac Vasc Anesth
May 2024
Institute of Anesthesiology, Herz- und Diabeteszentrum Nordrhein-Westfalen, Ruhr-University Bochum, Bad Oeynhausen, Germany. Electronic address:
Objectives: There is accumulating evidence that blood pressure management might be associated with end-organ dysfunction after cardiac surgery. This study aimed to investigate the impact of intraoperative hypotension (IOH) on adverse neurologic outcomes and mortality.
Design: A single-center retrospective cohort study.
Indian J Nephrol
March 2023
Department of Pediatrics, Bai Jerbai Hospital for Children, Mumbai, Maharashtra, India.
Introduction: Survival of tunneled cuffed catheters (TCC), used widely in children, is complicated by infections and catheter dysfunction. In resource limited settings, where risk of complications could be higher and waiting period for transplantation longer, catheter survival determines patient survival. This study was conducted to determine infection free catheter survival rates, incidence of catheter failure and associated risk factors.
View Article and Find Full Text PDFInt J Mol Sci
August 2023
IRCCS Fondazione Don Carlo Gnocchi, Via Capecelatro 66, 20148 Milan, Italy.
Better knowledge about the possible role of genetic factors in modulating the response to multiple sclerosis (MS) treatment, including rehabilitation, known to promote neural plasticity, could improve the standard of care for this disease. () gene polymorphisms are associated with MS risk, probably because of the role played by vitamin D in regulating inflammatory and reparative processes. The aim of this study was to evaluate the association of the most important functional SNPs ( (/), (/), and (/)) with functional outcome in MS patients undergoing multidisciplinary inpatient rehabilitation (MDR) treatment, in order to determine whether genetic profiling might be useful to identify subjects with a higher chance of recovery.
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