TCC in Transplant Ureter--When and When Not to Preserve the Transplant Kidney.

Am J Transplant

Department of Renal Transplantation and Pathology, Guy's Hospital, London, United Kingdom.

Published: February 2016

AI Article Synopsis

Article Abstract

We present four cases of transitional cell carcinoma of the transplant ureter (TCCtu). In three cases, localized tumor resection and a variety of reconstructive techniques were possible. Transplant nephrectomy with cystectomy was performed as a secondary treatment in one locally excised case. Transplant nephroureterectomy was performed as primary treatment in one case. The role of oncogenic viruses and genetic fingerprinting to determine the origin of TCCtu are described. Our cases and a systematic literature review illustrate the surgical, nephrological, and oncological challenges of this uncommon but important condition.

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajt.13533DOI Listing

Publication Analysis

Top Keywords

tcc transplant
4
transplant ureter--when
4
ureter--when preserve
4
transplant
4
preserve transplant
4
transplant kidney
4
kidney cases
4
cases transitional
4
transitional cell
4
cell carcinoma
4

Similar Publications

Transitional cell carcinoma (TCC) of the urinary tract appears more commonly among the transplant population. The increased incidence of TCC has been primarily associated with the male gender, BK virus (BKV), and smoking. We report a case series and comprehensive review of the literature.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluates clinical and oncological outcomes as well as renal function in patients who underwent radical cystectomy with pelvic lymphadenectomy for aggressive bladder cancer.
  • Out of 156 patients, 114 had high-grade transitional cell carcinoma, with 69.7% experiencing cancer recurrence post-surgery, mostly at distant sites.
  • The findings indicate a positive overall survival rate of 66.67% at 5 years, while pre-operative kidney function significantly affects post-operative renal outcomes.
View Article and Find Full Text PDF

Intraoperative Blood Pressure Management and Its Effects on Postoperative Delirium After Cardiac Surgery: A Single-Center Retrospective Cohort Study.

J Cardiothorac Vasc Anesth

May 2024

Institute of Anesthesiology, Herz- und Diabeteszentrum Nordrhein-Westfalen, Ruhr-University Bochum, Bad Oeynhausen, Germany. Electronic address:

Objectives: There is accumulating evidence that blood pressure management might be associated with end-organ dysfunction after cardiac surgery. This study aimed to investigate the impact of intraoperative hypotension (IOH) on adverse neurologic outcomes and mortality.

Design: A single-center retrospective cohort study.

View Article and Find Full Text PDF

Introduction: Survival of tunneled cuffed catheters (TCC), used widely in children, is complicated by infections and catheter dysfunction. In resource limited settings, where risk of complications could be higher and waiting period for transplantation longer, catheter survival determines patient survival. This study was conducted to determine infection free catheter survival rates, incidence of catheter failure and associated risk factors.

View Article and Find Full Text PDF

Better knowledge about the possible role of genetic factors in modulating the response to multiple sclerosis (MS) treatment, including rehabilitation, known to promote neural plasticity, could improve the standard of care for this disease. () gene polymorphisms are associated with MS risk, probably because of the role played by vitamin D in regulating inflammatory and reparative processes. The aim of this study was to evaluate the association of the most important functional SNPs ( (/), (/), and (/)) with functional outcome in MS patients undergoing multidisciplinary inpatient rehabilitation (MDR) treatment, in order to determine whether genetic profiling might be useful to identify subjects with a higher chance of recovery.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!