AI Article Synopsis
- The study aims to evaluate clinical protocols and automated workflows for using functional MRI in brain tumor patients before surgery.
- Results indicate that not all fMRI tasks are appropriate for individual patients, even if they yield positive group-level findings, and there’s a strong correlation between fMRI and direct electrical stimulation in identifying key brain areas.
- When reliable fMRI protocols are implemented, they can effectively help in identifying critical brain regions, aiding surgical planning for brain tumor treatment.
Article Abstract
Purpose: Present and assess clinical protocols and associated automated workflow for pre-surgical functional magnetic resonance imaging in brain tumor patients.
Methods: Protocols were validated using a single-subject reliability approach based on 10 healthy control subjects. Results from the automated workflow were evaluated in 9 patients with brain tumors, comparing fMRI results to direct electrical stimulation (DES) of the cortex.
Results: Using a new approach to compute single-subject fMRI reliability in controls, we show that not all tasks are suitable in the clinical context, even if they show meaningful results at the group level. Comparison of the fMRI results from patients to DES showed good correspondence between techniques (odds ratio 36).
Conclusion: Providing that validated and reliable fMRI protocols are used, fMRI can accurately delineate eloquent areas, thus providing an aid to medical decision regarding brain tumor surgery.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ijmedinf.2015.11.014 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!