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Effects of an intervention with EVOO and physical exercise in systemic lupus erythematosus patients: Efinutriles trial protocol.

Contemp Clin Trials

January 2025

Department of Nursing, Faculty of Health Sciences, University of Granada, 18071 Granada, Spain; MP07-Bases Fisiopatología y Terapéutica Médica, Instituto de Investigación Biosanitaria (ibs.GRANADA), 18014 Granada, Spain.

Article Synopsis
  • The study explores how combining extra virgin olive oil (EVOO) and a physical exercise program can potentially improve health outcomes for patients with systemic lupus erythematosus (SLE).
  • It involves a 24-week clinical trial with 90 participants split into three groups: a control group, one taking EVOO supplements, and one taking both EVOO and participating in a health promotion and exercise program.
  • The trial aims to assess various health metrics like disease activity, cardiovascular risk, and physical fitness, to determine if this combined approach offers significant benefits for SLE patients.
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Motivation: Despite lifestyle factors (LSFs) being increasingly acknowledged in shaping individual health trajectories, particularly in chronic diseases, they have still not been systematically described in the biomedical literature. This is in part because no named entity recognition (NER) system exists, which can comprehensively detect all types of LSFs in text. The task is challenging due to their inherent diversity, lack of a comprehensive LSF classification for dictionary-based NER, and lack of a corpus for deep learning-based NER.

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Integrative Bioinformatics Approaches to Uncover Hub Genes and Pathways Involved in Cardiovascular Diseases.

Cell Biochem Biophys

September 2024

Laboratory of Molecular and Cellular Screening Processes, Centre of Biotechnology of Sfax, University of Sfax, Sfax, Tunisia.

Cardiovascular diseases (CVD) represent a significant global health challenge resulting from a complex interplay of genetic, environmental, and lifestyle factors. However, the molecular pathways and genetic factors involved in the onset and progression of CVDs remain incompletely understood. Here, we performed an integrative bioinformatic analysis to highlight specific genes and signaling pathways implicated in the pathogenesis of 80 CVDs.

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A healthy lifestyle comprising regular physical activity and an adequate diet is imperative for the prevention of non-communicable diseases such as hypertension and some cancers. Advances in information computer technology offer the opportunity to provide personalised lifestyle advice directly to the individual through devices such as smartphones or tablets. The overall aim of the PROTEIN project (Wilson-Barnes et al.

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The compound eyes of insects exhibit stunning variation in size, structure, and function, which has allowed these animals to use their vision to adapt to a huge range of different environments and lifestyles, and evolve complex behaviors. Much of our knowledge of eye development has been learned from Drosophila, while visual adaptations and behaviors are often more striking and better understood from studies of other insects. However, recent studies in Drosophila and other insects, including bees, beetles, and butterflies, have begun to address this gap by revealing the genetic and developmental bases of differences in eye morphology and key new aspects of compound eye structure and function.

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