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Peak Weight Acceptance, Mid Stance Trough, and Peak Push-Off Force Symmetry Are Decreased in Older Adults Compared With Young Adults.
J Appl Biomech
January 2025
Department of Biomedical Engineering and Mechanics, Virginia Tech, Blacksburg, VA, USA.
Gait abnormalities affect an individual's ability to navigate the world independently and occur in 10% of older adults. Examining age-related gait symmetry in nonlaboratory environments is necessary for understanding mobility limitations in older adults. This study examined gait symmetry differences between older and younger adults using in-shoe force sensors.
View Article and Find Full Text PDFExamining tobacco use at the intersection of gender, sexual orientation, race, and ethnicity using national U.S. data of sexual and gender diverse youth.
Addict Behav
January 2025
University of Connecticut, Storrs, CT, USA.
Objectives: To expand the literature documenting that tobacco use inequities persist and continue to increase for minoritized youth populations by exploring patterns of tobacco use across multiple intersections of sexual, gender, racial, and ethnic identities. Studies with this focus are needed to understand the degree to which tobacco use varies across groups who hold multiple minoritized identities.
Methods: The current study used a novel analytical approach- Exhaustive Chi-square Automatic Interaction Detection - to examine lifetime cigarette use among a U.
Effects of Aging on Orbicularis Oculi Muscle Strength and Ultrastructure in Dermatochalasis: A Pilot Study.
J Clin Med
December 2024
Department of Neurology, National Institute of Medicine of the Ministry of Interior and Administration, 02-507 Warsaw, Poland.
Age-related changes to the orbicularis oculi muscle include impaired eyelid function, such as lagophthalmos, alterations in tear film dynamics, and aesthetic changes like wrinkles, festoons, and the descent of soft tissue. To date, the structural and functional changes that would comprehensively increase our understanding of orbicularis aging have not been analyzed. This study aims to investigate functional outcomes using surface electromyography and correlate them with ultrastructural changes in orbicularis during aging.
View Article and Find Full Text PDFElucidation of Factors Affecting the Age-Dependent Cancer Occurrence Rates.
Int J Mol Sci
December 2024
Systems Biology Laboratory for Metabolic Reprogramming, School of Medicine, Southern University of Science and Technology, Shenzhen 518055, China.
Cancer occurrence rates exhibit diverse age-related patterns, and understanding them may shed new and important light on the drivers of cancer evolution. This study systematically analyzes the age-dependent occurrence rates of 23 carcinoma types, focusing on their age-dependent distribution patterns, the determinants of peak occurrence ages, and the significant difference between the two genders. According to the SEER reports, these cancer types have two types of age-dependent occurrence rate (ADOR) distributions, with most having a unimodal distribution and a few having a bimodal distribution.
View Article and Find Full Text PDFThe Potential of Naturally Derived Compounds for Treating Chronic Kidney Disease: A Review of Autophagy and Cellular Senescence.
Int J Mol Sci
December 2024
Department of Medicine, Faculty of Medicine, University of Malaysia (UM), Kuala Lumpur 59100, Malaysia.
Article Synopsis
- Chronic kidney disease (CKD) is a progressive condition leading to kidney failure, and while there are treatments to manage it, none can reverse the damage.
- Traditional Chinese Medicine (TCM) offers an alternative with potentially fewer side effects, but more research is needed to understand how its natural products can help improve CKD, particularly in relation to mechanisms like autophagy and cellular aging.
- This review looks into TCM's natural products, their active components, and their possible roles in protecting kidney function and aiding in the management of CKD alongside conventional therapies.
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