Background: HBV infection is occupational risk for health care worker (HCW). They play an important role in dissemination of hepatitis B in society. This study aimed to assess Hepatitis B vaccination status of high transmitter risk group and their knowledge attitude and practice regarding Body substance Isolation.
Method: This questioner based cross sectional study was conducted in January 2013 to March 2014. 400 HCW comprising of 55% male and 45% female belonging to four groups 100 each doctor, nurse, Operation Theatre and clinical laboratory technician working at different tertiary hospitals in Karachi-Pakistan were included in the study.
Results: 28% doctors, 20% nurses, 64% operation theatre and 68% lab-technician were fully immunized. Among rest 31% were unaware of vaccine, 45% did not consider themselves among high risk group, 15% expected management to get them vaccinated, 9% found it expensive. Biosafety practices were correctly performed by 42%. 29% performed injection safe practice, 10% aseptic rules and 19% properly sterilized equipment. Blood spill was immediately cleaned by 80% among them 48% applied disinfectant, 40% cleaned it water and detergent, 12% cleaned and disinfected. Blood samples disposal was 52% in any available container, 17% in dustbin and 30% in biohazard bags. In case of accidental needle stick exposure 62 encouraged bleeding, 19% applied alcohol, 11% washed with water, 8% waited for medical help. Regarding discarding used syringe 42% used engineered device, 44% common container, 10% bent needles and 4% one handed scoop technique. Warning symbols were identified by 32% amongst them 30% identified biohazard, 8% harmful, 12% inflammable and 50% danger signs.
Conclusion: To prevent HCW from Hepatitis their complete immunization should be mandatory and rigid BSI protocol monitored daily.
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Lancet Reg Health Am
February 2025
World Trade Center Health Program, Renaissance School of Medicine, Stony Brook University, NY, USA.
Background: After surviving Coronavirus Disease 2019 (COVID-19), some people develop symptoms known as post-acute sequelae of COVID-19 (PASC). PASC is an emerging phenomenon yet to be fully understood, and identifying risk factors has been challenging. This study investigated the association between the number of COVID-19 episodes and the incidence of PASC among essential workers.
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Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, Sarawak, Malaysia.
Background: Public health campaigns are essential for promoting vaccination behavior, but factors such as socioeconomic status, geographical location, campaign quality, and service accessibility influence vaccine uptake. In the Wuxi region of China, disparities in vaccination behavior are seen between urban and rural populations and among different socioeconomic groups. This study aims to explore the factors related to public health campaigns that affect vaccination behavior in Wuxi, contributing to better public health strategies.
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Department of Clinical Laboratory Medicine, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Medicine and Health Key Laboratory of Laboratory Medicine, Jinan, 250000, China.
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Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei City, Taiwan.
Background: Since 2021, COVID-19 has had a substantial impact on global health and continues to contribute to serious health outcomes. In Taiwan, most research has focused on hospitalized patients or mortality cases, leaving important gaps in understanding the broader effects of the disease and identifying individuals at high risk. This study aims to investigate the risk factors for disease progression through a nationwide population-based cohort study on COVID-19 in Taiwan.
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January 2025
Emory Vaccine Center, Emory University, Atlanta, GA, USA; Emory National Primate Research Center, Atlanta, GA, USA; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA. Electronic address:
Infection with HIV is associated with dysregulated CD4 T cell responses to Mycobacterium tuberculosis (Mtb) and increased risk of developing tuberculosis. Mtb-specific CD4 T cells in people with HIV have diminished Th1 cytokine production capacity, thus we utilized a flow cytometry-based assay to measure CD40L expression by Mtb-specific CD4 T cells in a cytokine-independent manner. We evaluated the frequency and phenotype of Mtb-specific CD4 responses in Kenyan adults with latent Mtb infection and found that the majority of Mtb-specific CD4 T cells expressed CD40L in the absence of IFN-γ, regardless of HIV infection status.
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