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Helicobacter pylori-Related Chronic Gastritis as a Risk Factor for Lower Bone Mineral Density.
Calcif Tissue Int
January 2025
Department of Gastroenterology, School of Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, Wakayama, 641-0012, Japan.
We evaluated the role of Helicobacter pylori (H. pylori)-related chronic gastritis in the development of osteoporosis in a population-based study. A total of 1690 subjects in the cohort of the Research on Osteoarthritis/ osteoporosis Against Disability (ROAD) were investigated, and the association between gastritis and osteoporosis was evaluated by the presence of serologically assessed H.
View Article and Find Full Text PDFThe Landscape of Helicobacter pylori-related Gastric Carcinogenesis.
J Gastrointestin Liver Dis
December 2024
Department of Medicine, Pathology Unit, University of Padua, Padova 35121, Italy; Veneto Tumor Registry, Padova, Italy.
The relationship between Helicobacter pylori (H. pylori) and humans remains a complex enigma. While other factors contribute to gastric cancer (GC), their impact pales in comparison to the central role of H.
View Article and Find Full Text PDFEffect of -related chronic gastritis on gastrointestinal microorganisms and brain neurotransmitters in mice.
Front Pharmacol
December 2024
Institute of Gastroenterology, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.
The effects of (Hp)-related chronic gastritis on gastrointestinal microorganisms or brain neurotransmitters are not fully understood. Here, this study selected SPF C57BL/6 mice to set up a Hp-related chronic gastritis experiment group and a blank control group, and used omics to explore the specific effects of Hp-related chronic gastritis on gastrointestinal microorganisms and brain neurotransmitters in mice. The Tyramine (TyrA) content in the female experiment group's brain was considerably reduced compared to the female control group ( < 0.
View Article and Find Full Text PDFIdentification of core immune-related genes CTSK, C3, and IFITM1 for diagnosing Helicobacter pylori infection-associated gastric cancer through transcriptomic analysis.
Int J Biol Macromol
December 2024
Department of Microbiology, West China School of Basic Medical Sciences and Forensic Medicine, Sichuan University, Chengdu 610041, China. Electronic address:
Objectives: To identify diagnostic genes and mechanisms linking Helicobacter pylori (H. pylori) infection to gastric cancer.
Methods: Gene expression profiles from GEO were analyzed using differential expression gene (DEG) analysis, weighted gene co-expression network analysis (WGCNA), and functional enrichment.
Detection by Real-Time PCR of and Clarithromycin Resistance Compared to Histology on Gastric Biopsies.
Microorganisms
October 2024
Clinical Microbiology Department, CHC MontLégia, 4000 Liège, Belgium.
Article Synopsis
- The increase in gastric complications related to antimicrobial resistance has made accurate diagnosis and effective treatment essential.
- A study analyzed 232 gastric biopsy samples in the validation phase and 502 in the routine phase, using RT-PCR methods to test for bacterial presence and resistance.
- The RT-PCR tests showed 100% sensitivity for detection and significantly improved diagnostic efficiency over traditional culture and histology methods, identifying additional positive cases that histology missed.
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